DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and nek5

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	XP_005172616.3	Gene:	nek5 / 101885992	-ID:	-	Length:	244	Species:	Danio rerio

Alignment Length:	242	Identity:	111/242 - (45%)
Similarity:	157/242 - (64%)	Gaps:	5/242 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 LANYEKVRVVGQGSFGIAILY-RRKSDGHQIVFKQINLSELSPPGRDLAMNEVDVFSKLHHPNIV 165
            :..||.:|.:|||:||.|:|. ||:.|....|.|:|:|::||...::.:..||.:.||:.|||||
Zfish     2 MERYEVIRQIGQGAFGKALLVKRRRGDEQLYVIKEISLTQLSARDKEASRKEVTLLSKMKHPNIV 66

  Fly   166 SYLGSFIKDNTLLIEMEYADGGTLAQIIAERQGKLHFPERYIIAVFEQISSAINYMHSENILHRD 230
            ::..||...|.|.|.|||.|.|.|...|..::|| .|.|..|:..|.|:...:.::|...|||||
Zfish    67 AFHESFYDRNRLYILMEYCDSGDLMNRIKMQRGK-PFSEAQIVDWFVQMCLGLKHIHDRKILHRD 130

  Fly   231 LKTANVFLNRRGI-VKIGDFGISKIMNTKIH-AQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCI 293
            :|..||||.|.|: ||:|||||::::|:.:. .:|.:|||||.|||:||.|.|:||:|||:|||:
Zfish   131 IKAQNVFLTRGGLKVKLGDFGIARMLNSTMELVKTCVGTPYYLSPEICENKPYNNKTDIWSLGCV 195

  Fly   294 LGEMCCLKKTFAASNLSELVTKIMAGNYTPVPSGYTSGLRSLMSNLL 340
            |.|:|.|:..|..|:|.:||..|..|.:.||...|:|.|| ||.|||
Zfish   196 LYELCTLRHPFEGSSLKQLVLCICGGRFRPVSERYSSELR-LMLNLL 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	111/240 (46%)
		S_TKc	105..354	CDD:214567	111/239 (46%)
		ATS1	445..747	CDD:227511
nek5	XP_005172616.3	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D132059at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010