DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and nek11

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	XP_009290854.1	Gene:	nek11 / 101883026	ZFINID:	ZDB-GENE-100922-73	Length:	604	Species:	Danio rerio

Alignment Length:	250	Identity:	95/250 - (38%)
Similarity:	138/250 - (55%)	Gaps:	8/250 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 VGQGSFGIAILY---RRKSDGHQIVFKQINLSELSPPGRDLAMNEVDVFSKLHHPNIVSYLGSFI 172
            :|:||||...|.   :..::....|.|:|.:.:|.|.....|..|..:.|:|.||.|:.:..||:
Zfish    37 LGKGSFGTVYLVKDTKAVAEERLKVLKEIPVGDLKPNETVHATQEAQLLSQLSHPAILKFYSSFL 101

  Fly   173 KDNTLLIEMEYADGGTLAQIIAE--RQGKLHFPERYIIAVFEQISSAINYMHSENILHRDLKTAN 235
            :.:...|..|:.:...|...:.|  ..||. ..|..:.....|:...::|:|...|||||||..|
Zfish   102 ERDAFCIITEFCEDKDLDCKLEELKHTGKT-LSEPQVCEWLCQLLLGVHYIHQRRILHRDLKAKN 165

  Fly   236 VFLNRRGIVKIGDFGIS-KIMNTKIHAQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCILGEMCC 299
            :|| |:.||||||||:| .:|.:...|.|..|||||.|||....|.||:|||||:|||||.||||
Zfish   166 IFL-RKNIVKIGDFGVSCFLMGSCDLATTFTGTPYYMSPEALSHKGYDSKSDIWSLGCILYEMCC 229

  Fly   300 LKKTFAASNLSELVTKIMAGNYTPVPSGYTSGLRSLMSNLLQVEAPRRPTASEVL 354
            |...|.|.|...:|.:|:.|....:|..|:..|.|||.::|:.::..|.:|::.|
Zfish   230 LAHAFEAQNFLAVVLRIVEGPTPSLPETYSRQLNSLMQSMLEKDSSHRISAADAL 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	94/249 (38%)
		S_TKc	105..354	CDD:214567	94/248 (38%)
		ATS1	445..747	CDD:227511
nek11	XP_009290854.1	PKc_like	30..289	CDD:304357	94/249 (38%)
nek11	XP_009290854.1	S_TKc	31..289	CDD:214567	94/249 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D132059at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820