DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and nek5

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	XP_002936777.2	Gene:	nek5 / 100497645	XenbaseID:	XB-GENE-1012494	Length:	931	Species:	Xenopus tropicalis

Alignment Length:	347	Identity:	128/347 - (36%)
Similarity:	202/347 - (58%)	Gaps:	34/347 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 YEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGRDLAMNEVDVFSKLHHPNIVSYLG 169
            |:.||::|:|:||.|.|.:.|||..|.|.|:||||::....::.:..||.:.:|:.|||||::..
Frog     9 YDIVRMIGEGAFGKAYLAKGKSDNMQCVIKEINLSKMPTKEKEASHKEVVLLAKMKHPNIVTFFS 73

  Fly   170 SFIKDNTLLIEMEYADGGTLAQIIAERQGKLHFPERYIIAVFEQISSAINYMHSENILHRDLKTA 234
            |..:.|.|.|.|||.|||.|.:.:.:::|.| |.|..|::.|.|||..:.::|...:||||:|..
Frog    74 SIEERNKLYIVMEYCDGGDLMKRVNKQRGVL-FEEDQILSWFVQISLGLKHIHDRKVLHRDIKAQ 137

  Fly   235 NVFLNRRG-IVKIGDFGISKIMNTKIH-AQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCILGEM 297
            |:||:..| :.|:|||||::::|..:. |:|.:|||||.|||:||.|.|:||:|||:|||:|.|:
Frog   138 NIFLSNNGTLAKLGDFGIARMLNNTMELARTCVGTPYYLSPEICENKPYNNKTDIWSLGCVLYEL 202

  Fly   298 CCLKKTFAASNLSELVTKIMAGNYTPVPSGYTSGLRSLMSNLLQVEAPRRPTASEVLVYWIPLIF 362
            |.||..|.||:|.:||.||..|.|.|:|:.|:..||.|:|.|.::.:..||:.:.:|..  |.:.
Frog   203 CALKHPFEASSLRQLVLKICRGRYEPIPTKYSYDLRILVSQLFKISSRDRPSINSILKK--PFLE 265

  Fly   363 RSLGKNKGYS-YEDDVG-------GPGSDQLTAPVPAAAYSNVSMELELPTAQTE---TKQLMIA 416
            :.:.|:.... .|::..       .|.|:....|....         :||.|:.|   .::..|.
Frog   266 KRINKHLSPELIEEEFSHTVIHRKKPSSNPARYPCKPK---------QLPVAKVEVAKAERCKIR 321

  Fly   417 DTAAP---------HEILEKRS 429
            :..:|         .|:|.||:
Frog   322 EVNSPKPKVAVQPRREVLPKRN 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	112/255 (44%)
		S_TKc	105..354	CDD:214567	111/250 (44%)
		ATS1	445..747	CDD:227511
nek5	XP_002936777.2	PKc_like	8..264	CDD:389743	113/257 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D132059at33208
OrthoFinder	1	1.000	-	-		FOG0000168
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920