Protein Alignment niki and stkld1

DIOPT Version :10

• Sequence 1: NP_651293.1
• Gene: niki / 42959
• FlyBaseID: FBgn0045980
• Length: 841
• Species: Drosophila melanogaster
• Sequence 2: XP_031746904.1
• Gene: stkld1 / 100491915
• XenbaseID: XB-GENE-996507
• Length: 608
• Species: Xenopus tropicalis
• Alignment Length: 539
• Identity: 139/539 - (25%)
• Similarity: 224/539 - (41%)
• Gaps: 96/539 - (17%)

  Fly   104 NYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGRDLAMNEVDVFSKLHHPNIVSYL 168
            ||..:...|.|:||.|.|........|.|.|::..  :.....:||..|.....:|.||||.:|.
 Frog    21 NYRILEEWGPGTFGDACLVEELKGNTQYVIKKVEC--MDEREANLAAGEAAPLLRLRHPNICAYR 83

  Fly   169 GSFIK-DNTL-----LIEMEY-ADGGTLAQIIAERQGKLHFPERYIIAVFEQISSAINYMHSENI 226
            ..|:. ||.:     .:..:| |.|...|.:...||...:..|:.|..:..|..:|:.|:|.:|:
 Frog    84 EFFVTWDNKISALFFCLATDYCAHGDVAAMVRRNRQRVQNTEEKVIQVLLGQSINALIYIHQQNL 148

  Fly   227 LHRDLKTANVFLNRRGIVKIGDFGISKIMNTKIHAQTVLGTPY--YFSPEMCEGKEYDNKSDIWA 289
            |||:||.:|:||.......|||....::::.::..:..||..:  :.:||... ..|..|||:|:
 Frog   149 LHRNLKPSNIFLKDESTFLIGDLLPERLLSDEMRIEKRLGDEWRLWAAPEAMT-LTYSEKSDVWS 212

  Fly   290 LGCILGE-MCCLKKT--FAASNLSEL-VTKIMAGNYTP---VPSGYTSGLRSLMSNLLQVEAPRR 347
            |||:|.| |.|...|  ..||.|.|: ...:..|...|   ...||.:||..|:..:||:|..:|
 Frog   213 LGCVLLEVMSCSLYTGEMVASLLREIRAEPLCVGKLVPTLQAIGGYPAGLCQLLPLMLQIEPEKR 277

  Fly   348 PTASEVLVYWIPLIFRSLGKNKGYSYEDDVGGPGSDQ-LTAPVPAAA---YSNVSMELELPTAQT 408
            .||.|::  .:|.:.:.|..         :|...|.| .|.|..|.|   .:.|...||.....:
 Frog   278 CTAIELV--GVPYVKQCLAL---------IGSTLSGQKKTLPSGAIAELEEAGVEKTLEFMQRHS 331

  Fly   409 ETKQLMIADTAAPHEILEKRSVLYQLKAF-----GTCFSMAPIQLPPKAV-----IVDVAMSDSH 463
            :.:.   |.|||          :..|.|:     |.......|.|..:|:     .:|:.:..|.
 Frog   332 DFED---AQTAA----------ISHLSAYARHPDGLGHIEEIIALVVQAMRLHCSSLDILLDGSK 383

  Fly   464 FVVVNEDGSAYAWGEGTHGQ------LGLTALEAWKHYPSRME--SVRNYHVVSACAGDGFTILV 520
            .:   :|....|...|..|:      |.:|.:.|.:.:|..|.  ||....::..|..:..|.::
 Frog   384 LL---QDLLTQALEHGYEGESFTSNDLVVTLVAAARSFPHNMSLLSVIYRVIIILCTNEAATEML 445

  Fly   521 TQAGSLLS--------------CGSNAHL--ALGQDE---QR---NYHSPKLIARLA----DVRV 559
            .:||.|..              |.|...|  ::|..|   ||   ...:|:::..|:    |..|
 Frog   446 GKAGFLEGVAKIMGRVLQSREMCVSCCRLLWSIGTAEGSPQRVWLELAAPRILPLLSGYMGDPPV 510

  Fly   560 EQVAAGLQHVLALSREGAV 578
            .:||.|...::.|  :|.|
 Frog   511 VEVACGALWIMCL--KGCV 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	82/270 (30%)
		ATS1	433..749	CDD:444065	41/190 (22%)
stkld1	XP_031746904.1	Protein Kinases, catalytic domain	21..289	CDD:473864	83/272 (31%)