Protein Alignment niki and nek2

DIOPT Version :10

• Sequence 1: NP_651293.1
• Gene: niki / 42959
• FlyBaseID: FBgn0045980
• Length: 841
• Species: Drosophila melanogaster
• Sequence 2: NP_001164656.1
• Gene: nek2 / 100328980
• XenbaseID: XB-GENE-29077543
• Length: 442
• Species: Xenopus tropicalis
• Alignment Length: 364
• Identity: 119/364 - (32%)
• Similarity: 193/364 - (53%)
• Gaps: 47/364 - (12%)

  Fly    77 MPNRQESLLQLSVPRETGVGVAGPELANYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSEL 141
            ||:|.|                     :||.:..:|.||:|.....||:|||..:|:|:::...:
 Frog     1 MPSRVE---------------------DYEVLYTIGSGSYGKCQKIRRRSDGKLLVWKELDYGTM 44

  Fly   142 SPPGRDLAMNEVDVFSKLHHPNIVSYLGSFI--KDNTLLIEMEYADGGTLAQIIA----ERQGKL 200
            :...:.:.::||::..:|.|||||.|....|  .:.||.|.|||.:||.||.:||    |||
 Frog    45 TEAEKQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASLIAKCTKERQ--- 106

  Fly   201 HFPERYIIAVFEQISSAINYMHSEN-----ILHRDLKTANVFLNRRGIVKIGDFGISKIM-NTKI 259
            :..|.:|:.:|.|::.|:...|..:     :||||||.||:||:.:..||:||||:::|: :...
 Frog   107 YLEEDFILRIFSQLALALKDCHKRSDGGHTVLHRDLKPANIFLDAKNNVKLGDFGLARILHHDSS 171

  Fly   260 HAQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCILGEMCCLKKTFAASNLSELVTKIMAGNYTPV 324
            .|:|.:|||||.|||......|:.|||||:|||:|.|:|.|...|.|.|..||..||..|.:..:
 Frog   172 FAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALSPPFTAYNQKELAEKIREGRFRRI 236

  Fly   325 PSGYTSGLRSLMSNLLQVEAPRRPTASEVLVYWIPLIFRSLGKNKGYSYEDDVGGPGSDQLTAPV 389
            |..|:..|..:::|:|.::...||:..|:|.:  .|:...:.:.:..:.:..:.....::|:.|.
 Frog   237 PYRYSEELNQVITNMLHLKDYLRPSIEEILQH--HLLAELVREEQKKTEKKVLRAAEQERLSMPD 299

  Fly   390 PAAAYSNVSMELELPTAQTETKQLMIADTAAPHEILEKR 428
            |      |..||.|...|..|::..:.:.   .|.||:|
 Frog   300 P------VPSELRLKEQQLHTRERALRER---EERLEQR 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	101/266 (38%)
		ATS1	433..749	CDD:444065
nek2	NP_001164656.1	STKc_Nek2	7..271	CDD:270857	101/268 (38%)