DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and LOC100328980

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_001164656.1	Gene:	LOC100328980 / 100328980	-ID:	-	Length:	442	Species:	Xenopus tropicalis

Alignment Length:	364	Identity:	119/364 - (32%)
Similarity:	193/364 - (53%)	Gaps:	47/364 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 MPNRQESLLQLSVPRETGVGVAGPELANYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSEL 141
            ||:|.|                     :||.:..:|.||:|.....||:|||..:|:|:::...:
Frog     1 MPSRVE---------------------DYEVLYTIGSGSYGKCQKIRRRSDGKLLVWKELDYGTM 44

  Fly   142 SPPGRDLAMNEVDVFSKLHHPNIVSYLGSFI--KDNTLLIEMEYADGGTLAQIIA----ERQGKL 200
            :...:.:.::||::..:|.|||||.|....|  .:.||.|.|||.:||.||.:||    |||
Frog    45 TEAEKQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASLIAKCTKERQ--- 106

  Fly   201 HFPERYIIAVFEQISSAINYMHSEN-----ILHRDLKTANVFLNRRGIVKIGDFGISKIM-NTKI 259
            :..|.:|:.:|.|::.|:...|..:     :||||||.||:||:.:..||:||||:::|: :...
Frog   107 YLEEDFILRIFSQLALALKDCHKRSDGGHTVLHRDLKPANIFLDAKNNVKLGDFGLARILHHDSS 171

  Fly   260 HAQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCILGEMCCLKKTFAASNLSELVTKIMAGNYTPV 324
            .|:|.:|||||.|||......|:.|||||:|||:|.|:|.|...|.|.|..||..||..|.:..:
Frog   172 FAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALSPPFTAYNQKELAEKIREGRFRRI 236

  Fly   325 PSGYTSGLRSLMSNLLQVEAPRRPTASEVLVYWIPLIFRSLGKNKGYSYEDDVGGPGSDQLTAPV 389
            |..|:..|..:::|:|.::...||:..|:|.:  .|:...:.:.:..:.:..:.....::|:.|.
Frog   237 PYRYSEELNQVITNMLHLKDYLRPSIEEILQH--HLLAELVREEQKKTEKKVLRAAEQERLSMPD 299

  Fly   390 PAAAYSNVSMELELPTAQTETKQLMIADTAAPHEILEKR 428
            |      |..||.|...|..|::..:.:.   .|.||:|
Frog   300 P------VPSELRLKEQQLHTRERALRER---EERLEQR 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855	101/266 (38%)
		S_TKc	105..354	CDD:214567	100/260 (38%)
		ATS1	445..747	CDD:227511
LOC100328980	NP_001164656.1	STKc_Nek2	7..271	CDD:270857	101/268 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D132059at33208
OrthoFinder	1	1.000	-	-		FOG0000168
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010