DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment niki and herc5.3

DIOPT Version :9

Sequence 1:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	XP_021330683.1	Gene:	herc5.3 / 100073325	ZFINID:	ZDB-GENE-070615-14	Length:	1002	Species:	Danio rerio

Alignment Length:	321	Identity:	75/321 - (23%)
Similarity:	117/321 - (36%)	Gaps:	95/321 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   454 IVDVAMSDSHFVVVNEDGSAYAWGEGTHGQLGLTALEAWKHYPSRMESVRNYHVVSACAGDGFTI 518
            ::.:|..|.|.:.:..||..:.|||...|||||
Zfish   123 VIQIACGDQHSMALTNDGQLFVWGENALGQLGL-------------------------------- 155

  Fly   519 LVTQAGSLLSCGSNAHLALGQDEQRNYHSPKLIARLADVRVEQVAAGLQHVLALSREGAVYVWGT 583
                                :.||....||:.:..|..:.|.|::||..|...||..|.|:.||:
Zfish   156 --------------------RKEQAGTQSPQHLQSLCGIPVAQISAGGNHSFVLSLSGVVFGWGS 200

  Fly   584 STCGALGLGNYQQQQKFPQKILLSHVKTKPSKIYCGPDTSAVLFANGELHVCGSNDYNKLGFQRS 648
            ::.|.||||:  ...:|...|:.|....|...|.||.:.:|.|...|.:...||..:.:||.
Zfish   201 NSAGQLGLGD--TTDRFIPTIVKSLSGKKTVSISCGGEHTATLSKGGTVFTFGSGGFGQLGH--- 260

  Fly   649 AKITAFKKVQLPH--------KVTQACFSSTHS-VFLVEGGYVYTMGRNAEGQ--RGIRHCNSVD 702
               .:.|....|.        ||:|......|: ||......:|:.|...:||  .|.:...||.
Zfish   261 ---NSLKDEHHPRLVAELWGSKVSQVTCGRHHTLVFEDSSNQIYSFGCGMQGQLGNGEQVKQSVP 322

  Fly   703 HPTLVDSVKSRYIVKANCSDQCT------IVASEDNIITVW----GTRNGLPGIGSTNCGL 753
            .|.|:.:             :||      ::|.|::...::    |..:..|..|| |.|:
Zfish   323 LPVLLPT-------------ECTEFTMEKLIAGENHSFALFFKSPGNESEKPKSGS-NGGI 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855
		S_TKc	105..354	CDD:214567
		ATS1	445..747	CDD:227511	71/313 (23%)
herc5.3	XP_021330683.1	RCC1	<74..349	CDD:332518	69/298 (23%)
herc5.3	XP_021330683.1	HECTc	665..1000	CDD:331829
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920