DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Saf-B and AtRZ-1c

DIOPT Version :9

Sequence 1:	NP_733041.2	Gene:	Saf-B / 42958	FlyBaseID:	FBgn0039229	Length:	928	Species:	Drosophila melanogaster
Sequence 2:	NP_196048.1	Gene:	AtRZ-1c / 830307	AraportID:	AT5G04280	Length:	310	Species:	Arabidopsis thaliana

Alignment Length:	518	Identity:	108/518 - (20%)
Similarity:	152/518 - (29%)	Gaps:	228/518 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly   314 LWVSGLSTLTRASDLKAIFSKFGKVIGAKVVTNTRTPGTRCYGYVTMSSSADASRCIENLHRTEL 378
            ::|.|||......||:..||:||.::..:::....|..:|.:|::|.:........|..:|..:.
plant     9 IFVGGLSPEVTDRDLERAFSRFGDILDCQIMLERDTGRSRGFGFITFADRRAMDESIREMHGRDF 73

  Fly   379 HGRIISVERTKNEIGGSLNSKEGKGKAPGDAGNKKKEDDSGKKSGSGKGSSSNSGDDKKGGDGNG 443
            ..|:|||.|.:.::|      ...|::.|..|.:    ||| .|.:||||.        ||.|.|
plant    74 GDRVISVNRAEPKLG------RDDGESHGSRGGR----DSG-YSIAGKGSF--------GGGGGG 119

  Fly   444 DSKSVGGDLKRD-----GKESNRARS--RRNDDRGKSLASQDRPRHDRERSAKGSQDHRSGRNPR 501
                 ||.:..|     |:..:.||.  .....||..:..     .....||.|..|.|
plant   120 -----GGRVGEDECFKCGRVGHWARDCPSAGGGRGGPVGG-----FSSRASAYGGSDGR------ 168

  Fly   502 DVDREIQQRQRERERRQREMLSYQKIREERERQRLRERERELREEERRRREARERQRIEEERLQE 566
             |||                      ..:|:|...|||..:.|.:...|..||:|         .
plant   169 -VDR----------------------YADRDRYVDRERYIDDRYDGAARYGARDR---------F 201

  Fly   567 ERRKLAVERERLEREKAELLRMERERQKLEREKIELERLELKRQQMKIMESRDDPGKRGVSKRAD 631
            :.|:..:.|:|.                                                   |.
plant   202 DSREAYIPRDRY---------------------------------------------------AS 215

  Fly   632 DRYGDVTDRKRTAIFDAPPPPRFDTNLVSSRSTYDKKHDDYGSSSSTKRVLDDYSSSSKRLDYSS 696
            |||             |.|..||...                         |.||..|.|
plant   216 DRY-------------AAPADRFAGG-------------------------DRYSRGSDR----- 237

  Fly   697 KRNDYSSSSGSKRGAVDDYTAVPTKRSNDYSASSSSKRDDYKRDEVRHLPLSGTVGGGSSSSYLH 761
                                         |...|..|...::||..   |.:|      |..|
plant   238 -----------------------------YPPGSYDKARSFERDIA---PSAG------SDRY-- 262

  Fly   762 KNNTAGGGAGSYVHKNNTSGTGGRYNDSDRSNTSSYRRDDSHSLGNKRYDNSSGGGGAYGSSS 824
                .||.||..:......|.|.|    .|:. :.|.|           .:.|||||||.|||
plant   263 ----GGGRAGGPIRGGGEEGRGFR----SRAG-APYER-----------PSRSGGGGAYPSSS 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Saf-B	NP_733041.2	SAP	11..42	CDD:280251
		RRM	205..>394	CDD:223796	21/79 (27%)
		RRM_SAFB_like	313..386	CDD:240863	19/71 (27%)
		SWIRM-assoc_1	<588..618	CDD:293104	0/29 (0%)
AtRZ-1c	NP_196048.1	RRM	8..80	CDD:214636	18/70 (26%)
AtRZ-1c	NP_196048.1	zf-CCHC	128..143	CDD:395050	3/14 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	87	1.000	Inparanoid score	I2315
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050