| Sequence 1: | NP_733041.2 | Gene: | Saf-B / 42958 | FlyBaseID: | FBgn0039229 | Length: | 928 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001188267.1 | Gene: | SAFB / 6294 | HGNCID: | 10520 | Length: | 917 | Species: | Homo sapiens |
| Alignment Length: | 1037 | Identity: | 291/1037 - (28%) |
|---|---|---|---|
| Similarity: | 438/1037 - (42%) | Gaps: | 264/1037 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 3 EAG-KKIAELRVCDLKSELEKRELETVGPKAVLIERLEKSLRAEGLDPATHLIVP---------G 57
Fly 58 AKAKKPFAMPMKDLQSEVVIKEEPIDANE-EEVKVEQQDDYQNGNDYSHHADD------DGHEID 115
Fly 116 QVGDVDDECVILDDDDEEDEDHVYDDEPQSGDGD--------AEGKAQDDGAENNGD----DKAI 168
Fly 169 IHGEEENT------------GDTGNMD--NDESINL---------TIGED----EQKLLHDEA-- 204
Fly 205 -SDDKSIKSVKPAN-KSEKSNS------KDADKKNDDGARS-------KKRDEKSGDKKDSSEQK 254
Fly 255 S----------------SGKSSNQKDDKEKSTAAPGGATSSTASSAAGSKSGSGSSAGNGTGANS 303
Fly 304 NNK-QATLSRNLWVSGLSTLTRASDLKAIFSKFGKVIGAKVVTNTRTPGTRCYGYVTMSSSADAS 367
Fly 368 RCIENLHRTELHGRIISVERTKNEIGGSLNSKEGKGKAPGDAGNKKKEDDSGKKSGSGKGSSSNS 432
Fly 433 GDD-KKGGDGNGDSKSVGGDLKRDGKESNRARSRRNDDRG-KSLASQDRPR----------HDRE 485
Fly 486 RSAKGSQDHRSGRNPRDVDREIQQRQRERERRQREMLSYQKIREERE------RQRLRER-EREL 543
Fly 544 REEERRRREARERQRIEEERLQEERRKLAVERERLEREKAELLRM--ERERQKLEREKIELERLE 606
Fly 607 LKRQQMKIMESRDDPGKRGVSKRADDRYGDVTDRKRTAIFDAPPPPRFDTNLVSSRSTYDKKHDD 671
Fly 672 YGSSSSTKRVLDDYSSSSKRLDYSSKRNDYSSSSGSKRGAVDDYTAVPTKRSNDYSASSSSKRDD 736
Fly 737 YKRDEVRHLPLSGTVGGGSSSSYLHKNNTAGGGAGSYVHKNNTSGTG------GRYNDSDRSNTS 795
Fly 796 SYRRDDSHSLGNKRYDNSSGGGGAYGSSSNSVNIWAPSSGGSSSHLGSGGGGGNQIKSYGNNGMS 860
Fly 861 SNMHSTNSWQKSAPVDDNGWRQVPARFDRGYNERSTGYQGQSGGGGAGGMYGASRPAQDRYS 922 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Saf-B | NP_733041.2 | SAP | 11..42 | CDD:280251 | 17/30 (57%) |
| RRM | 205..>394 | CDD:223796 | 78/219 (36%) | ||
| RRM_SAFB_like | 313..386 | CDD:240863 | 49/72 (68%) | ||
| SWIRM-assoc_1 | <588..618 | CDD:293104 | 15/31 (48%) | ||
| SAFB | NP_001188267.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..33 | 2/7 (29%) | |
| SAP | 31..65 | CDD:128789 | 17/33 (52%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 64..118 | 14/67 (21%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 221..407 | 34/185 (18%) | |||
| RRM_SAFB1_SAFB2 | 405..480 | CDD:241123 | 50/74 (68%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 477..641 | 55/188 (29%) | |||
| Interaction with POLR2A. Interaction with SFRS1, SFRS9 and SFRS10. /evidence=ECO:0000250|UniProtKB:O88453, ECO:0000269|PubMed:9671816 | 528..792 | 95/344 (28%) | |||
| Nuclear localization signal. /evidence=ECO:0000255 | 599..616 | 5/16 (31%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 671..708 | 17/41 (41%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165143756 | |
| Domainoid | 1 | 1.000 | 114 | 1.000 | Domainoid score | I6072 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG4661 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 298 | 1.000 | Inparanoid score | I2724 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S4174 |
| OMA | 1 | 1.010 | - | - | QHG46608 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0005622 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41150 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | LDO | PTHR15683 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1765 |
| SonicParanoid | 1 | 1.000 | - | - | X1802 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 13 | 12.840 | |||||