DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Saf-B and tra2b

DIOPT Version :9

Sequence 1:	NP_733041.2	Gene:	Saf-B / 42958	FlyBaseID:	FBgn0039229	Length:	928	Species:	Drosophila melanogaster
Sequence 2:	NP_001006878.1	Gene:	tra2b / 448667	XenbaseID:	XB-GENE-5864557	Length:	293	Species:	Xenopus tropicalis

Alignment Length:	315	Identity:	72/315 - (22%)
Similarity:	120/315 - (38%)	Gaps:	67/315 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   207 DKSIKSVKPANKSEKSNSKDADKKNDDGARSKKRDEKSGDKKDSSEQKSSGKSSNQKDDKEKSTA 271
            |:..:|...:..:.:|....:...|...|||:.: |.|...:..:..:|..:|.:::..:...|
Frog    11 DRESRSASRSGSARQSGKSASQSPNHSAARSRSK-EGSRHSRSKTRSRSDSRSRSRRSSRRHYT- 73

  Fly   272 APGGATSSTAS-SAAGSKSGSGSSAGNGTGANSNNKQATLSRN------------LWVSGLSTLT 323
                 .|.|.| |...|:|.|.|.......::|::..:|..|:            |.|.|||..|
Frog    74 -----RSRTRSRSRRRSRSRSHSRDYRRRRSHSHSPMSTRRRHVGNRANPDPNCCLGVFGLSLYT 133

  Fly   324 RASDLKAIFSKFGKVIGAKVVTNTRTPGTRCYGYVTMSSSADASRCIENLHRTELHGRIISVERT 388
            ...||:.:|||:|.:....:|.:.::..:|.:.:|...:..||....|..:..||.||.|.|:.:
Frog   134 TERDLREVFSKYGPISDVSIVYDQQSRRSRGFSFVYFENVDDAKEAKERANGMELDGRRIRVDFS 198

  Fly   389 KNEIGGSLNSKEGKGKAPGDAGNKKKEDDSGKKSGSGKGSSSNSGDDK-------KGGDGNGDSK 446
                    .:|......||....:.....|.::....:|......||:       :||.|.|
Frog   199 --------ITKRPHTPTPGIYMGRPTYGSSRRRDYYDRGYDRGGYDDREYYSRSYRGGGGGG--- 252

  Fly   447 SVGGDLKRDGKESNRARSRRNDDRGKSLASQDRPRHDRERS-----AKGSQDHRS 496
              ||                  .||    .|||.:..|.||     ::||...||
Frog   253 --GG------------------WRG----GQDRDQFSRRRSPSPYYSRGSYRSRS 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Saf-B	NP_733041.2	SAP	11..42	CDD:280251
		RRM	205..>394	CDD:223796	47/199 (24%)
		RRM_SAFB_like	313..386	CDD:240863	23/84 (27%)
		SWIRM-assoc_1	<588..618	CDD:293104
tra2b	NP_001006878.1	RRM_SF	113..201	CDD:388407	24/95 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1765
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030