DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Saf-B and rbfox1l

DIOPT Version :9

Sequence 1:	NP_733041.2	Gene:	Saf-B / 42958	FlyBaseID:	FBgn0039229	Length:	928	Species:	Drosophila melanogaster
Sequence 2:	NP_999940.1	Gene:	rbfox1l / 407613	ZFINID:	ZDB-GENE-040923-2	Length:	382	Species:	Danio rerio

Alignment Length:	175	Identity:	52/175 - (29%)
Similarity:	78/175 - (44%)	Gaps:	29/175 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 GDKKDSSEQKSSGKSSNQKDDKEKSTAAPGGATSSTASSAAGSKSGSGSSAGNGTGANSNNKQAT 309
            |.:.|.:|   |..:||..|.....|:.|   .|.:.|.|:||.:..||....|..|.
Zfish    94 GPQHDGTE---SITASNTDDSLAPVTSDP---QSLSVSVASGSGAAGGSDEEGGGKAQ------- 145

  Fly   310 LSRNLWVSGLSTLTRASDLKAIFSKFGKVIGAKVVTNTRTPGTRCYGYVTMSSSADASRCIENLH 374
             .:.|.||.:....|..||:.:|.:|||::..:::.|.|  |::.:|:||..|:.:|.|..|.|:
Zfish   146 -PKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNER--GSKGFGFVTFESAVEADRAREKLN 207

  Fly   375 RTELHGRIISVER------TK-------NEIGGSLNSKEGKGKAP 406
            .|.:.||.|.|..      ||       |..|..:|...|...||
Zfish   208 GTIVEGRKIEVNNATARVVTKKPQTPLVNAAGWKINPVMGAMYAP 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Saf-B	NP_733041.2	SAP	11..42	CDD:280251
		RRM	205..>394	CDD:223796	47/161 (29%)
		RRM_SAFB_like	313..386	CDD:240863	25/72 (35%)
		SWIRM-assoc_1	<588..618	CDD:293104
rbfox1l	NP_999940.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	34..79
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	94..148		18/67 (27%)
		RRM	<143..>237	CDD:223796	29/103 (28%)
		RRM_FOX1_like	147..222	CDD:240853	26/76 (34%)
		Fox-1_C	257..353	CDD:289199
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000