DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Saf-B and SPAC25G10.01

DIOPT Version :9

Sequence 1:	NP_733041.2	Gene:	Saf-B / 42958	FlyBaseID:	FBgn0039229	Length:	928	Species:	Drosophila melanogaster
Sequence 2:	NP_001342863.1	Gene:	SPAC25G10.01 / 3361412	PomBaseID:	SPAC25G10.01	Length:	297	Species:	Schizosaccharomyces pombe

Alignment Length:	287	Identity:	65/287 - (22%)
Similarity:	121/287 - (42%)	Gaps:	59/287 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 KDADKKNDDG---ARSKKRDEKSGDKKDS-SEQKSSGKSSNQKDDKEKSTAAPGGATSSTASSAA 285
            |||.:.:.|.   |.:..:.:.:|:...| :|.:....:.:...||::..:||.|:.:
pombe    41 KDAGETDSDAGSIAMNVHQLDTAGEPLQSMNEDEVDPNNESTALDKKEPQSAPEGSEN------- 98

  Fly   286 GSKSGSGSSAGNGTGANSNNKQATLSRNLWVSGLSTLTRASDLKAIFSKFGKVIGAKVVTNTRTP 350
                                    |..:|:|||:::..:..:|:.||||||.|...:::....|.
pombe    99 ------------------------LGNDLFVSGIASRMQEDELQQIFSKFGTVTHVRIMREPVTK 139

  Fly   351 GTRCYGYVTMSSSADASRCIENLHRTELHGRIISVERTKNEIGGSLNSKEGKGKAPG-DAGNKKK 414
            .:|.:|:::.|:..:|:..|:||:..|.:||:::|::.|.    |.......||..| |.....:
pombe   140 ASRGFGFLSFSTVEEATSAIDNLNSQEFYGRVLNVQKAKR----SRPHSPTPGKYMGYDRRRNSR 200

  Fly   415 EDDSGKKSGSGKGSSSNSGDDKKGGDGNGDSKSVGGDLKRDGKESNRARSRRNDDRGKSLASQDR 479
            :..|..|.|..:.::....|..:..:....|:.     :|:....|..:.|.|.|        .|
pombe   201 DFPSNNKDGGYRRNNYRDRDSNRYRNSYRPSRP-----QREHSPGNYRKERYNVD--------SR 252

  Fly   480 PRHDRERSAKGSQ----DHRSGRNPRD 502
            ||  |||...|..    :|.|..|.|:
pombe   253 PR--RERHFHGRSFAHAEHHSVPNMRN 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Saf-B	NP_733041.2	SAP	11..42	CDD:280251
		RRM	205..>394	CDD:223796	39/172 (23%)
		RRM_SAFB_like	313..386	CDD:240863	23/72 (32%)
		SWIRM-assoc_1	<588..618	CDD:293104
SPAC25G10.01	NP_001342863.1	RRM	9..>225	CDD:223796	48/218 (22%)
		RRM_RBMX_like	100..179	CDD:240828	24/78 (31%)
		RRM	207..>283	CDD:330708	20/86 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto101110
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1765
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030