Protein Alignment Saf-B and Safb2

DIOPT Version :9

• Sequence 1: NP_733041.2
• Gene: Saf-B / 42958
• FlyBaseID: FBgn0039229
• Length: 928
• Species: Drosophila melanogaster
• Sequence 2: NP_001290073.1
• Gene: Safb2 / 301126
• RGDID: 1588577
• Length: 991
• Species: Rattus norvegicus
• Alignment Length: 1012
• Identity: 279/1012 - (27%)
• Similarity: 432/1012 - (42%)
• Gaps: 266/1012 - (26%)

  Fly     6 KKIAELRVCDLKSELEKRELETVGPKAVLIERLEKSLRAEGLDPATHLIVPGAKAKKPFAMPMKD 70
            :::::|||.||::||:||.|:|.|.|:||:|||:|:.:.||.:|....|..||.:|:......|.
  Rat    23 RRLSDLRVIDLRAELKKRNLDTGGNKSVLMERLKKAFKEEGQEPEEVGISWGAVSKRAIKRNTKG 87

  Fly    71 LQSE------VVIKEEPIDANEEEVKVEQQDDYQNGNDYSHHADDDGHEIDQV-------GDVDD 122
            .:.|      ..::|:..|..:|.|.::...|    .|.......||.|...:       .|.|.
  Rat    88 AKMEEEGGEDTGLEEDSRDGQDETVILQSSQD----RDTVDTGVPDGMEAQDLSVPCLGKADTDK 148

  Fly   123 ECVILDDDDEE------------------DEDHVYDD--------------------EPQS---- 145
            :.:...||.:|                  :|| |:.:                    ||::
  Rat   149 QSLDAFDDSKEYVAAQLGQLPAQLLKHAVNED-VFKNTLEASMSDLKVTMAGEEAPLEPENEKIL 212

  Fly   146 ---GDGDAEGKAQDDGAE----------NNGDDKAIIHGEEENTGDT-GNMDNDESINLTIGEDE 196
               |:.......:::|:|          :.|.|:.:  .|||:..:: |:.:.:|       |:|
  Rat   213 DILGETCKSEPVKEEGSELEQPFAQATSSVGPDRKL--AEEEDLFESCGHPEEEE-------EEE 268

  Fly   197 QKLLHDEASDDKSIKSVKPANKSEKSNSK----DAD------KKNDDGA----------RSKKRD 241
            ::...:|..:::...::..::|||.|:::    :||      |:....|          |.:||.
  Rat   269 EEEEQEEEQEEEGDLALASSSKSESSSTRCQWSEADALLAVVKREPAEAPGGGGGTQHWRKRKRR 333

  Fly   242 EKSGDK-------------------KDSSEQKS---------------------SGKSSNQKDDK 266
            .|...:                   ::..||.|                     |.:..:.|||.
  Rat   334 RKHQAEAEALGTGGGTWMNREPVGLEEPVEQSSTAAQLPEATSQELVRAPTAAPSPEPRDSKDDV 398

  Fly   267 EK-----STAAPGGATSSTASSAAGSKSGSGSSAGNGTGANSNNK-QATLS--RNLWVSGLSTLT 323
            :|     ....|.....|:||..|..|........:......:.| :|:.|  |||||||||:.|
  Rat   399 KKFAFDACNDVPAAPKESSASEGADQKMSFVKEEQDIKPVIKDEKGRASCSSGRNLWVSGLSSST 463

  Fly   324 RASDLKAIFSKFGKVIGAKVVTNTRTPGTRCYGYVTMSSSADASRCIENLHRTELHGRIISVERT 388
            ||:|||::|||.|||||||||||.|:||.||||:||||.|.:|::||.:|||||||||:||||:.
  Rat   464 RAADLKSLFSKHGKVIGAKVVTNARSPGARCYGFVTMSMSDEATKCINHLHRTELHGRMISVEKA 528

  Fly   389 KNEIGGSLNSK----EGKGKAPG-DAGNK----------KKEDDSGKKSGSGKGSSSNSGDDKKG 438
            |||.....::.    :.|.|.|| |..:.          |||:...:|...|........|..:.
  Rat   529 KNEPSEKKSADRRACDQKEKVPGPDRPHPVKIKMEKTVIKKEEKLERKEEKGPEDIKKEKDQDEL 593

  Fly   439 GDGNGDSKSVGGDLKRDGKESNRARSR---RNDDRGKSLASQDRPRHDRERSAKGSQDHRS-GRN 499
            ..|......|       .|..:|...|   .:..:|:.:.|.......::||:| |||.:| ||.
  Rat   594 PPGTASHSRV-------TKSGSRCTERTVVMDKSKGEPVISVKATSRSKDRSSK-SQDRKSEGRE 650

  Fly   500 PRDVDREIQQRQRERERRQREMLSYQKIREERERQRLRERERELREEERRR-REARER------- 556
            .||:                  ||:.||:|:|||:|.|:||||:||.|||| ||.|||
  Rat   651 KRDI------------------LSFDKIKEQRERERQRQREREIRETERRREREQREREQRLDAF 697

  Fly   557 -QRIEEERLQEERRKLAVERERLEREKAELLRMERERQKLERE------KIELERLELKRQQMKI 614
             :|.|:.|||.||.:|..:|:|||||:.|..|:||||.::|||      :|..||.||:|||.::
  Rat   698 QERREKARLQRERLQLQCQRQRLERERLERERLERERMRVERERRKEQQRIMREREELRRQQEQL 762

  Fly   615 --------------MESRDDPGKRGVSKRA--DDRYGDV-TDRKRTAIFDAPPPPRFDTNLV--- 659
                          :::|.|.|.....|||  :|||.|. ....|...||......:..:::
  Rat   763 RAEQERRALRRAYNLDARRDDGYWPEGKRAAMEDRYRDFPRPDHRFHDFDHRERGHYQEHVIDRR 827

  Fly   660 -SSRSTYDKKHDDYGSSSSTKRVLDDYSSSSKRLDYS--SKRNDYSSSSGSKRGAVDDYTAVPTK 721
             .||...:::...|        ..||..|..:.|::.  ..|:.:...|..|:.........|.:
  Rat   828 DGSRPRMEERDGPY--------YPDDQHSHGRPLEHHGWDARDGWHGYSSDKKLNEGLGLPPPPR 884

  Fly   722 RSNDYSASSSSKRD----------DYKRDEVRHLPLSGTVGGGSSSSYLHKNNTAGG--GAGSYV 774
            .|.:::..||...:          |.......|:...|...|.:...:.|.....||  |.||:.
  Rat   885 VSREWAEHSSQLEEQQVPVWHNAVDTNMTGHEHIRWRGAERGLTGPGHGHVAAGRGGMAGQGSFA 949

  Fly   775 HKNNTSG--------TGGRYNDSDRSNTSSYRRDDSH 803
            |..::.|        .||.....|:..    |..:||
  Rat   950 HGEHSQGHIMPSGRLEGGGVASQDQGG----RIPNSH 982

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Saf-B	NP_733041.2	SAP	11..42	CDD:280251	19/30 (63%)
		RRM	205..>394	CDD:223796	89/256 (35%)
		RRM_SAFB_like	313..386	CDD:240863	54/72 (75%)
		SWIRM-assoc_1	<588..618	CDD:293104	15/49 (31%)
Safb2	NP_001290073.1	SAP	25..58	CDD:128789	18/32 (56%)
		RRM	399..>541	CDD:223796	70/141 (50%)
		RRM_SF	451..526	CDD:302621	55/74 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	113	1.000	Domainoid score	I5974
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46608
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005622
OrthoInspector	1	1.000	-	-		otm45291
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15683
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1802
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.020