Protein Alignment Saf-B and Saf-B

DIOPT Version :10

• Sequence 1: NP_733041.2
• Gene: Saf-B / 42958
• FlyBaseID: FBgn0039229
• Length: 928
• Species: Drosophila melanogaster
• Sequence 2: XP_061507877.1
• Gene: Saf-B / 1281879
• VectorBaseID: AGAMI1_002320
• Length: 1080
• Species: Anopheles gambiae
• Alignment Length: 1130
• Identity: 431/1130 - (38%)
• Similarity: 552/1130 - (48%)
• Gaps: 300/1130 - (26%)

  Fly     2 PEAGKKIAELRVCDLKSELEKRELETVGPKAVLIERLEKSLRAEGLDPATHLIVPGAKAKKPFAM 66
            ||. :|::||||.|||.|||||..:..|.|.||:|||.::||.|||||.|
Mosquito    38 PEK-RKLSELRVVDLKLELEKRGKDGNGVKNVLLERLTQTLRDEGLDPET--------------- 86

  Fly    67 PMKDLQSEVVIKEEPIDANEEEVKVEQQDDYQNGNDYSHHADDDGHEIDQVGDVDDECVILDDDD 131
                       .|..|.|.:..||..:.......::.|....|.....:|..|..:.....:|..
Mosquito    87 -----------MEFEIAAGKASVKKVRASTGGKTDEESGSTADAAASSEQNADSTETSQPAEDSK 140

  Fly   132 EEDEDHVYDDEP--QSGDGDAE------GKAQD------------DGAENNGDDKAIIHGEEEN- 175
            ..||      ||  ::|.|..|      |||.|            :.||....:|..:..:::.
Mosquito   141 ASDE------EPAVENGKGTEEKEEQLNGKATDATQPEESVEKESEAAEEPAQEKVSVEEKKDEF 199

  Fly   176 -------------------------TGDTGNMDNDESINLTIGEDEQKLLHD-----EASDDKSI 210
                                     ..|:...||::|:||||||:::|||||     |..::::.
Mosquito   200 VKPTESVPQEKVVAPKQEESKPVDLKEDSKEADNEDSLNLTIGEEDEKLLHDSNMEVEQKEEETQ 264

  Fly   211 KSVKPANKSEKSNSKDADKKNDDGARSK-------KRDEKSG--DKKDSSEQKSSGKSSNQKDDK 266
            |..:.:.|::::.|:|: |||||....|       ...||.|  .|..:|...||..:|::...:
Mosquito   265 KKEQSSAKAKENASEDS-KKNDDKREGKIEKSVVTSSTEKDGAATKTTASSSSSSTAASSRSGGE 328

  Fly   267 EKSTAAPGGATSSTASSAAGSKSGSGSSAGNGTGANSNNKQATLSRNLWVSGLSTLTRASDLKAI 331
            :.:||:|...|:|||:||:.:..|...:.|.|:....:...|.:|||||||.||:||||:|||.|
Mosquito   329 KATTASPASTTNSTAASASTTAGGDDKTKGGGSTDGGSGSAANVSRNLWVSRLSSLTRATDLKQI 393

  Fly   332 FSKFGKVIGAKVVTNTRTPGTRCYGYVTMSSSADASRCIENLHRTELHGRIISVERTKNEIGGSL 396
            |||:|||||||||||:|||||||||||||:|:.||:.||.:|||||||||:|||||.|:|:|.:.
Mosquito   394 FSKYGKVIGAKVVTNSRTPGTRCYGYVTMASAKDATECINHLHRTELHGRLISVERAKSELGPAR 458

  Fly   397 NSKEGKGKAPGDAGNKKKEDDSGKKSGSG-------KGSSSNSGDD-KKGGD------------- 440
            :|..|...:...|......:.|||.||:|       |.|||.|..| ||.||
Mosquito   459 SSSTGADSSSAKATTASSSNASGKGSGTGGKSDTKPKSSSSTSNSDKKKNGDVSKTSANAADKDR 523

  Fly   441 ----------------------------------GNGDSKSVGGDLKRDGKES--NRARSRRNDD 469
                                              |.|.|:| ||.....|::|  ..|.:|::.|
Mosquito   524 KPAPKDRAKPATAAAPARPARAPASDGKRPSTAGGTGTSRS-GGASGTGGEKSGGGAAAARKSTD 587

  Fly   470 RGKSLASQDRPRHDRERSAKGSQDHRSGRNPRDVDREIQQRQR----------ERERRQ-REMLS 523
              ...||..|...||.||::..:.:..|.:.:..||  |||.|          ||:.|: ||:||
Mosquito   588 --NVAASAGRRSRDRSRSSRDRRSNTHGSSSQVRDR--QQRSRGSSRGAAGPKERDSRESREVLS 648

  Fly   524 YQKIREERERQRLRERERELREEERRRREARERQRIEEERLQEERRKLAVERERLEREKAELLRM 588
            .|||||||||.|||||||:||||||||||.|.|||.||||||.||.|||.||||:|:|||||||:
Mosquito   649 LQKIREERERHRLRERERQLREEERRRREIRARQREEEERLQREREKLAAERERIEKEKAELLRI 713

  Fly   589 ERERQKLEREKIELERLELKRQQMKIMESRDDPGKRGVSKRADDRYGDVTDRKRTA---IFDAPP 650
            .||||||||||||||.||||:||.||.|:     ||.:.:.:.|||.|  ||||.|   ..:|||
Mosquito   714 VRERQKLEREKIELEHLELKQQQRKIEEA-----KRSLKRPSTDRYDD--DRKRPAPDRRVEAPP 771

  Fly   651 PPRFDTNLVSS---RSTYDKKHDDYGSSSSTKRVLDDY----SSSSKRLDY---SSKRNDYSSSS 705
            |||||:::.||   ||.||:.     .|:..|..||||    ||||||.|:   :.||.|.....
Mosquito   772 PPRFDSSITSSSGRRSNYDRI-----PSTDKKSRLDDYPASSSSSSKRDDFRRDTFKRGDDYRRG 831

  Fly   706 GS--KRGAVDDYTAVPTKRS---------NDYSASSSSKRDDY--------KRDEVRHLPLS--- 748
            |.  |||. |||     |||         :||.:|..| .|||        |||..|  |:|
Mosquito   832 GDDYKRGG-DDY-----KRSGDDFKRDSRDDYKSSGRS-GDDYGKRDSGYSKRDLDR--PISSSY 887

  Fly   749 ----GTVGGGSSSSYL------------HKNNTAGGGAG----SYVHKNNTSGTGGRYNDSDRSN 793
                |..|||..|..|            ..|:..|||.|    |....|..||.|||.:|.||:|
Mosquito   888 DSRGGGGGGGGGSGLLSQSLSKEGRYSDRSNDYRGGGGGISGSSGGGLNGGSGGGGRGDDRDRNN 952

  Fly   794 TSSYRRDDSHSLGNKRYDNSSG---GGGAYGSSSNSVNIWAPSS----GGSSSHLGSGGGGGNQI 851
            :||.|      .||.|....:|   |||.:.||:....|...||    |..::..|||||||
Mosquito   953 SSSSR------YGNDRTSGGNGTASGGGNWHSSAGLSQISGISSLGNWGDKTNDGGSGGGGG--- 1008

  Fly   852 KSYGNNGMSSNMHSTNSWQKSAPVDDNGWRQVPARFDRGYNER-----STGYQGQSGGGGAGGMY 911
                             |:..    |||    ..|:||.||||     |:| .|..||||.||..
Mosquito  1009 -----------------WRNM----DNG----QDRYDRTYNERKPMPMSSG-GGGGGGGGGGGFM 1047

  Fly   912 GASRP----------AQDRYSGPVS 926
            ..|||          .||||...:|
Mosquito  1048 DQSRPNQFMGGSGGRPQDRYGQSMS 1072

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Saf-B	NP_733041.2	SAP	11..42	CDD:460424	18/30 (60%)
		2A1904	<16..>270	CDD:273344	80/313 (26%)
		RRM_SF	311..386	CDD:473069	60/74 (81%)
		SWIRM-assoc_1	<588..618	CDD:465142	23/29 (79%)
Saf-B	XP_061507877.1	None