DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Saf-B and Tra2a

DIOPT Version :9

Sequence 1:	NP_733041.2	Gene:	Saf-B / 42958	FlyBaseID:	FBgn0039229	Length:	928	Species:	Drosophila melanogaster
Sequence 2:	XP_006505303.1	Gene:	Tra2a / 101214	MGIID:	1933972	Length:	309	Species:	Mus musculus

Alignment Length:	301	Identity:	77/301 - (25%)
Similarity:	121/301 - (40%)	Gaps:	44/301 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 VKPANKSEKSNSKDADKKND--DGARSKKRDEKSGDKKDSSEQKSSGKS---SNQKDDKEKSTAA 272
            |:..::|:......|..|::  .|:||..|..|..:....|..||..:|   |:::..:.:|.:.
Mouse    39 VESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSH 103

  Fly   273 PGGATS-STASSAAGSKSGSGSSAGN---GTGANSNNKQATLSRNLWVSGLSTLTRASDLKAIFS 333
            ...:.| |........:|.|.|...|   .||:.:|....|.   |.|.|||..|...||:.:||
Mouse   104 RRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTC---LGVFGLSLYTTERDLREVFS 165

  Fly   334 KFGKVIGAKVVTNTRTPGTRCYGYVTMSSSADASRCIENLHRTELHGRIISVERTKNEIGGSLNS 398
            ::|.:.|..||.:.||..:|.:.:|......|:...:|..:..||.||.|.|:.:        .:
Mouse   166 RYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYS--------IT 222

  Fly   399 KEGKGKAPGDAGNKKKEDDSGKKSGSGKGSSSNSGDDKKGGDGNGDSKSVGGDLKRDG---KESN 460
            |......||..        .|:.:.||.|.....|    ||.|.|     ||..:||.   :..:
Mouse   223 KRAHTPTPGIY--------MGRPTHSGGGGGGGGG----GGGGGG-----GGGRRRDSYYDRGYD 270

  Fly   461 RARSRRNDDRGKSLASQDRPRHDRERSAKGSQDHRSGRNPR 501
            |...|..|...:.......|.:.|.||...|:.:    :||
Mouse   271 RGYDRYEDYDYRYRRRSPSPYYSRYRSRSRSRSY----SPR 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Saf-B	NP_733041.2	SAP	11..42	CDD:280251
		RRM	205..>394	CDD:223796	51/189 (27%)
		RRM_SAFB_like	313..386	CDD:240863	25/72 (35%)
		SWIRM-assoc_1	<588..618	CDD:293104
Tra2a	XP_006505303.1	RRM_TRA2	143..222	CDD:409798	27/89 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1765
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030