Protein Alignment Saf-B and srsf4

DIOPT Version :10

• Sequence 1: NP_733041.2
• Gene: Saf-B / 42958
• FlyBaseID: FBgn0039229
• Length: 928
• Species: Drosophila melanogaster
• Sequence 2: XP_004911639.2
• Gene: srsf4 / 100038227
• XenbaseID: XB-GENE-493077
• Length: 741
• Species: Xenopus tropicalis
• Alignment Length: 794
• Identity: 171/794 - (21%)
• Similarity: 291/794 - (36%)
• Gaps: 183/794 - (23%)

  Fly     7 KIAELRVCDLKS-----ELE-KRELETVGPKAVLIERLEKSLRAEGLDPATHLIVPGAKAKKPFA 65
            ||.|:   |||:     |.| .|:.|.     .:.|...:.|..|      .:||..|:|
 Frog    32 KIVEV---DLKNGYGFVEFEDSRDAED-----AVYEMNGRELCGE------RVIVEHARA----- 77

  Fly    66 MPMKDLQSEVVIKEEPIDANEEEVK---------VEQQDDYQNGNDYSHHADD----DGHEIDQV 117
             |.:|::|....::...|.....|:         :..:..:|:..|:...|.:    |.|:..|
 Frog    78 -PRRDIRSGYGYRKGGSDKYGPPVRTMYRLRVENLSSRCSWQDLKDFMRQAGEVTYADAHQRRQ- 140

  Fly   118 GDVDDECVILDDDDEEDEDHVYDDEPQSGDGDAEGKAQDDGAENNGDDKAIIHGEEENTGDTGNM 182
                :|.||        |...|.|..::.:       :.||:|.||....::   |:..|.....
 Frog   141 ----NEGVI--------EFRSYSDMRRALE-------KLDGSEINGRKIQLV---EDRAGSRNKG 183

  Fly   183 DNDESINLTIGEDEQKLLHDEASDDKS---IKSVKPANKSEKSNSKDADKKNDDGARSKKRDEKS 244
            .:..|      ....:.....:|..:|   .:|...:.:.|:|.|:..::::......|:|:.:|
 Frog   184 SSSRS------RSRSRSRRSRSSHSRSRSRSRSHSRSRQRERSRSRSKERRSSRSHSRKRRESRS 242

  Fly   245 -GDKKDSSEQKSSGKSSNQKDDKEK--STAAPGGATSSTASSAAGSKSGSGSSAGNGTGANSNNK 306
             ..::..|...|.|:.:::...|.:  |.:...|..:|.:.|.....|.|.|.....:.:.|..:
 Frog   243 ISKRRRQSRSVSKGRRASRSVSKGRRASRSVSKGRRASRSVSKGRRASRSVSKGRRASRSVSKGR 307

  Fly   307 QATLSRNLWVSGLSTLTRASDLKAIFSKFGKVIGAKVVTNTRTPGTRCYGYVTMSSSADASRCIE 371
            :|:.|.:   .|......||..:.......|   .:..:.:.:.|.|.      |.||...|
 Frog   308 RASRSAS---KGRRASRSASKGRRASRSASK---GRRASRSASKGRRA------SRSASKGR--- 357

  Fly   372 NLHRTELHGRIISVERTKNEIGGSLNSKEGKGKAPGDAGNKKKEDDSGKKSGSGKGSSSNSG--D 434
            ...|:...||..|...:|   |...:....||:....:.:|::........|.....|::.|  :
 Frog   358 RASRSASKGRRASRSASK---GRRASRSASKGRRASRSASKERRASRSASKGRRTSRSASKGRQE 419

  Fly   435 DKKGGDGNGDSKSVGGDLKRDGKESNRARSR-RNDDRGKSLASQDRPRHDRERSAKGSQDHRSGR 498
            .:....|..:|:||.     .|:..:|:.|: |.:.|..|...::.....:||  :||.||..||
 Frog   420 SRSVSKGRRESRSVS-----KGRRESRSVSKGRRESRSVSKGRRETRSVSKER--RGSSDHSKGR 477

  Fly   499 ----------NPRD--VDREIQQRQRERERRQREMLSYQKIREER-----ERQRLRERERELREE 546
                      |.||  .|.| :.:.|.|.|.:||..|..|.|:||     ||.|.|.:||.|...
 Frog   478 ASRSQSKDRANGRDKSADSE-RSKSRSRSRGRRETDSQSKERKERVSRSTERSRSRSKERRLSRS 541

  Fly   547 ERRRREARERQRIEEERLQEERRKLAVERERLEREKAELLRMERERQKLEREKIELERLELKRQQ 611
            ..|.::.| .:..|.:.|...:|..:..|||..|.|             :|:.|
 Frog   542 NSRDKKGR-NESTERQELNSRKRDRSHSRERRNRSK-------------DRDHI----------- 581

  Fly   612 MKIMESRDDPGKRGVSKRADDRYGDVTDRKRTAIFDAPPPPRFDTNLVSSRSTYDKKHDDYGSSS 676
                        |...|.:.:|   ..||||:...|            .||....|:..|...|.
 Frog   582 ------------RSKDKHSRNR---SRDRKRSRSRD------------RSRERQSKRSRDRSRSK 619

  Fly   677 STKRVLDDYSSSSKRLDYSSKRN---DYSSSSGSKRGAVDDYTAVPTKRSNDYSASSSSKRDDYK 738
            ...|..:....||:..:.|.||:   ..||:..||:...:|..|..|:     |...:...:..|
 Frog   620 ERSRRSERSRRSSRSKERSRKRSRERRSSSAERSKKVKREDTVAFTTE-----SDQEAENEEGSK 679

  Fly   739 RDEVRHLPLSGTVG 752
            .:.|:|   :.|:|
 Frog   680 AEVVQH---AETIG 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Saf-B	NP_733041.2	SAP	11..42	CDD:460424	8/36 (22%)
		2A1904	<16..>270	CDD:273344	51/278 (18%)
		RRM_SF	311..386	CDD:473069	15/74 (20%)
		SWIRM-assoc_1	<588..618	CDD:465142	2/29 (7%)
srsf4	XP_004911639.2	RRM_SF	6..77	CDD:473069	16/58 (28%)
		RRM_SF	104..176	CDD:473069	18/94 (19%)
		PTZ00121	<248..716	CDD:173412	120/529 (23%)
		PRK12678	255..>469	CDD:237171	46/238 (19%)