DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5808 and CPR4

DIOPT Version :9

Sequence 1:	NP_651291.1	Gene:	CG5808 / 42957	FlyBaseID:	FBgn0027617	Length:	653	Species:	Drosophila melanogaster
Sequence 2:	NP_009995.1	Gene:	CPR4 / 850433	SGDID:	S000000665	Length:	318	Species:	Saccharomyces cerevisiae

Alignment Length:	242	Identity:	50/242 - (20%)
Similarity:	90/242 - (37%)	Gaps:	60/242 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DLTVDLFISERPIACLNFLKLCR-----LKYYNFNLFHT----------------VQQGFIAQTG 54
            |||.:|:.:..|....||..|..     ::..:.|..||                :|.|.:|...
Yeast    67 DLTFELYGTVVPKTVNNFAMLAHGVKAVIEGKDPNDIHTYSYRKTKINKVYPNKYIQGGVVAPDV 131

  Fly    55 DPSGAGDGGSSIWGVVEGPQKRFFEAEFLPKINHSSAGMLSLVSAGKNLVGSQFFLTL-GENLTS 118
            .|.           .|.||  :|.:..|.  :.|.....|::...|.:...|:|.:|. .:....
Yeast   132 GPF-----------TVYGP--KFDDENFY--LKHDRPERLAMAYFGPDSNTSEFIITTKADGNEE 181

  Fly   119 LDGNHCVIGEVVEGHEVLRKLNDAI----VDDSFRPYQDIRITHTVVLEDPFPNPRGLQAPSRSP 179
            |||...|.|::..|   |.:|.|||    .|:..:|..::|..:.|:......|...|.|   :.
Yeast   182 LDGKSVVFGQITSG---LDQLMDAIQYTETDEYGKPQHELRFLYFVLEILKISNILDLHA---AY 240

  Fly   180 SPSAERLKNGRIAADEDIDD-------------TDGMTAEEMQEMLA 213
            :...|:.:||.::....:::             :.|.||.::...::
Yeast   241 TEKVEKFRNGDVSVGSTLENIFRNDKAYTPLTTSTGTTAYDLNHPIS 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5808	NP_651291.1	cyclophilin_RRM	4..169	CDD:238902	41/183 (22%)
		RRM	<237..445	CDD:223796
		RRM_PPIL4	237..319	CDD:240681
CPR4	NP_009995.1	cyclophilin	67..219	CDD:238194	39/169 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810