Protein Alignment CG5808 and Cwc27

DIOPT Version :10

• Sequence 1: NP_651291.1
• Gene: CG5808 / 42957
• FlyBaseID: FBgn0027617
• Length: 653
• Species: Drosophila melanogaster
• Sequence 2: NP_001347023.1
• Gene: Cwc27 / 67285
• MGIID: 1914535
• Length: 472
• Species: Mus musculus
• Alignment Length: 609
• Identity: 148/609 - (24%)
• Similarity: 239/609 - (39%)
• Gaps: 176/609 - (28%)

  Fly     3 VVIETTMGDLTVDLFISERPIACLNFLKLCRLKYYNFNLFHTVQQGFIAQTGDPSGAGDGGSSIW 67
            |:::||.||:.::|:..|.|.||.||::||...||:..:||.|..|||.|.|||:|.|.||.||:
Mouse    15 VLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVPGFIVQGGDPTGTGTGGESIY 79

  Fly    68 GVVEGPQKRFFEAEFLPKINHSSAGMLSLVSAGKNLVGSQFFLTLGENLTSLDGNHCVIGEVVEG 132
            |..       |:.||..::..:..|::::.:||.:..|||||.||| ....|:..|.:.|:|. |
Mouse    80 GAP-------FKDEFHSRLRFNRRGLVAMANAGPHDNGSQFFFTLG-RADELNNKHTIFGKVT-G 135

  Fly   133 HEV--LRKLNDAIVDDSFRPYQDIRITHTVVLEDPFPN--PRGLQAPSRSPSPSAERLKNGRIAA 193
            ..|  :.:|.:..:||..||....||....||.:||.:  ||.::.|           ||.:
Mouse   136 DTVYNMLRLTEVDIDDEERPRNPHRIKSCEVLFNPFDDITPREIKKP-----------KNEK--- 186

  Fly   194 DEDIDDTDGMTAEEMQEMLAEREAKARATILEIVGDLPDADMAPPENVLFVCKLNPVTTDDDLEI 258
                               .|.|.|                           ||.|..|.:
Mouse   187 -------------------PEEEVK---------------------------KLKPKGTKN---- 201

  Fly   259 IFS--SFGVLKGCEVIRDRKTGDSLQYAFVEFEDQKSCEAAYFKMDNVLIDDRRIHVDFSQSVSK 321
             ||  |||                     .|.|:::                        :.|::
Mouse   202 -FSLLSFG---------------------EEAEEEE------------------------EEVNR 220

  Fly   322 VTWRGKGRGIEGDYRKLDFNNLRDDKDHRKPNNGRSRTEDHKERNRTEDFRNRMSSAERRKAREQ 386
            |:...|||.      |...:.|:||     |:.......:.::.:.|.|..:.:...|...|...
Mouse   221 VSQSMKGRS------KSSHDLLKDD-----PHLSSVPAVESEKDDATGDLEDLLQDGEDDSAERD 274

  Fly   387 RHQEQSERDVRKNLQRRTRSKEKDEKSVYRSKKSQNESVRENSNR-ERNRNEKR-------SSRS 443
            .:.|..|    |||.|. |..::.:|....|.||..:..::.::| |..|.|.|       :::.
Mouse   275 EYMEDDE----KNLMRE-RIAKRLKKDASASVKSAGDGEKKPASRSEELRKEARQLKRELLAAKQ 334

  Fly   444 RDATHRRYSRSRDREERRPSRPRDQLGRRSRSRDQKERRRSRPREQNERRRSRSRDQTGKRPTQN 508
            :..|..:....|:.||..|.      |..:..|.:|::..:..::|.::..|| .|||....:|.
Mouse   335 KKETAIKVEEGREEEEAAPD------GAVAEYRREKQKYEALRKQQPKKGTSR-EDQTLALLSQF 392

  Fly   509 RDRNDSRRFHSPQ----EGRRNDER---SHRETSRNQRRSPERRQQSRNREDHRMDTHS--SPNK 564
            :.:.......:|:    |....|:.   ||    ..|.....|:.:..:.:|  .||..  .|..
Mouse   393 KSKLTQAITETPENSVPEAEVEDDEGWMSH----VLQFEDKTRKVKDASMQD--SDTFEIYDPRN 451

  Fly   565 SHEKKRKLSVEKSKK--QAKKSKR 586
            ...|:|:   |:|||  :.||.:|
Mouse   452 PVNKRRR---EESKKLLREKKERR 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5808	NP_651291.1	cyclophilin_RRM	4..169	CDD:238902	63/168 (38%)
		RRM_PPIL4	237..319	CDD:409681	11/83 (13%)
		PRK12678	344..>510	CDD:237171	38/173 (22%)
		U2AF_lg	467..>572	CDD:273727	23/113 (20%)
Cwc27	NP_001347023.1	cyclophilin_CeCYP16-like	8..178	CDD:238906	65/171 (38%)
		CWC27_CTD	376..428	CDD:412084	12/56 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	431..472		13/45 (29%)