DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5808 and ppib

DIOPT Version :9

Sequence 1:	NP_651291.1	Gene:	CG5808 / 42957	FlyBaseID:	FBgn0027617	Length:	653	Species:	Drosophila melanogaster
Sequence 2:	NP_998184.1	Gene:	ppib / 406292	ZFINID:	ZDB-GENE-040426-1955	Length:	216	Species:	Danio rerio

Alignment Length:	163	Identity:	58/163 - (35%)
Similarity:	85/163 - (52%)	Gaps:	15/163 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 GDLTVDLFISERPIACLNFLKLCRLKY---YNFNLFHTVQQGFIAQTGD-PSGAGDGGSSIWGVV 70
            |.:.:.||....|....|||:|...:.   |..:.||.|.:.|:.|.|| ..|.|.||.||:|
Zfish    58 GRIVIGLFGKTVPKTTENFLQLATGEKGFGYKGSKFHRVIKDFMIQGGDFTRGDGTGGKSIYG-- 120

  Fly    71 EGPQKRFFEAEFLPKINHSSAGMLSLVSAGKNLVGSQFFLTLGENLTSLDGNHCVIGEVVEGHEV 135
                .||.:..|  |:.|...|.||:.:|||:..|||||:|..:. ..|||.|.|.|:::||.:|
Zfish   121 ----DRFPDENF--KLKHYGPGWLSMANAGKDTNGSQFFITTVQT-PWLDGKHVVFGKILEGMDV 178

  Fly   136 LRKLNDAIVDDSFRPYQDIRI--THTVVLEDPF 166
            :||:.....|...:|.:|:.|  :..:.:|.||
Zfish   179 VRKIEATKTDGRDKPLKDVSIHDSGKIDVEKPF 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5808	NP_651291.1	cyclophilin_RRM	4..169	CDD:238902	58/163 (36%)
		RRM	<237..445	CDD:223796
		RRM_PPIL4	237..319	CDD:240681
ppib	NP_998184.1	cyclophilin_ABH_like	45..203	CDD:238907	55/153 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900