DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5808 and CG7747

DIOPT Version :9

Sequence 1:	NP_651291.1	Gene:	CG5808 / 42957	FlyBaseID:	FBgn0027617	Length:	653	Species:	Drosophila melanogaster
Sequence 2:	NP_611113.1	Gene:	CG7747 / 36820	FlyBaseID:	FBgn0034109	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	241	Identity:	85/241 - (35%)
Similarity:	126/241 - (52%)	Gaps:	34/241 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VVIETTMGDLTVDLFISERPIACLNFLKLCRLKYYNFNLFHTVQQGFIAQTGDPSGAGDGGSSIW 67
            |.:.|.:|.|.::||..:.|.||.||:|.|...|||..:||...:.||.|.|||:|:|.||.|||
  Fly   282 VRLNTNLGPLNLELFCDQTPRACDNFIKHCANGYYNNVMFHRSIRNFIVQGGDPTGSGSGGESIW 346

  Fly    68 GVVEGPQKRFFEAEFLPKINHSSAGMLSLVSAGKNLVGSQFFLTLGENLTSLDGNHCVIGEVVEG 132
            |       :.||.||.|.:.|:..|:||:.::|.|..|||||:|. .:...|||.|.:.|::|.|
  Fly   347 G-------KKFEDEFKPNLTHTGRGVLSMANSGPNTNGSQFFITY-RSCKHLDGKHTIFGKLVGG 403

  Fly   133 HEVLRKLNDAIVDDSFRPYQDIRITHTVVLEDPFPNPRGLQAPSRSPSPSAERLKNGR---IAAD 194
            .:.|:|:.:..||:..||.:||.|..:.|..:||             :.:||:|...|   .|..
  Fly   404 LDTLQKMENIEVDNKDRPIEDIIIESSQVFVNPF-------------AEAAEQLAKEREEEAAGK 455

  Fly   195 EDIDDTDGMTAEEMQEMLAE-----REAKARATILEIVGDLPDADM 235
            |:|     :..||.|:.:.|     ||...:...|:.|...|:|.:
  Fly   456 EEI-----VKKEEQQKRMKEPLKVYREGVGKYLKLQTVAKKPEAPL 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5808	NP_651291.1	cyclophilin_RRM	4..169	CDD:238902	67/164 (41%)
		RRM	<237..445	CDD:223796
		RRM_PPIL4	237..319	CDD:240681
CG7747	NP_611113.1	RING	25..238	CDD:302633
CG7747	NP_611113.1	cyclophilin_RING	281..439	CDD:238904	68/177 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447184
Domainoid	1	1.000	81	1.000	Domainoid score	I449
eggNOG	1	0.900	-	-		E1_COG0652
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.740