DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5808 and PPIL6

DIOPT Version :9

Sequence 1:	NP_651291.1	Gene:	CG5808 / 42957	FlyBaseID:	FBgn0027617	Length:	653	Species:	Drosophila melanogaster
Sequence 2:	NP_001104768.2	Gene:	PPIL6 / 285755	HGNCID:	21557	Length:	337	Species:	Homo sapiens

Alignment Length:	198	Identity:	61/198 - (30%)
Similarity:	96/198 - (48%)	Gaps:	39/198 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSVVIETT-MGDLTVDLFISERPIACLNFLKLC-----------RLKYYNFNLFH-TVQQGFIAQ 52
            :.:.|::: :|.|..:|:....|..|.||..||           ||.|.| ::|| .||.|:| |
Human   146 LDICIDSSPIGRLIFELYCDVCPKTCKNFQVLCTGKAGFSQRGIRLHYKN-SIFHRIVQNGWI-Q 208

  Fly    53 TGD-PSGAGDGGSSI--------WGVVEGPQKRFFEAEFLPKIN----------HSSAGMLSLVS 98
            .|| ..|.||.|.||        :|.::...||..|:..:.||.          |:..|:|.:.:
Human   209 GGDIVYGKGDNGESIYGPTFEELYGSLKRSVKRQKESRGVGKIEKYRDENFSVPHNKRGVLGMAN 273

  Fly    99 AGKNLVGSQFFLTLGENLTSLDGNHCVIGEVVEGHEVLRKLNDAIVDDSFRPYQDIRITHTVVLE 163
            .|::..||||::|| :....||......|:::||.|||::| :.:...:.||....|||.:   .
Human   274 KGRHSNGSQFYITL-QATPYLDRKFVAFGQLIEGTEVLKQL-ELVPTQNERPIHMCRITDS---G 333

  Fly   164 DPF 166
            ||:
Human   334 DPY 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5808	NP_651291.1	cyclophilin_RRM	4..169	CDD:238902	61/195 (31%)
		RRM	<237..445	CDD:223796
		RRM_PPIL4	237..319	CDD:240681
PPIL6	NP_001104768.2	cyclophilin	144..333	CDD:412213	59/193 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810