DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5808 and PPIL2

DIOPT Version :9

Sequence 1:NP_651291.1 Gene:CG5808 / 42957 FlyBaseID:FBgn0027617 Length:653 Species:Drosophila melanogaster
Sequence 2:XP_011528343.1 Gene:PPIL2 / 23759 HGNCID:9261 Length:616 Species:Homo sapiens


Alignment Length:257 Identity:77/257 - (29%)
Similarity:117/257 - (45%) Gaps:54/257 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 VVIETTMGDLTVDLFISERPIACLNFLKLCRLKYYNFNLFHTVQQGFIAQTGDPSGAGDGGSSIW 67
            |.:.|..|||.::|.....|..|.||::||:..||:..:||...:.|:.|.|||:|.|.||.|.|
Human   282 VRLHTNKGDLNLELHCDLTPKTCENFIRLCKKHYYDGTIFHRSIRNFVIQGGDPTGTGTGGESYW 346

  Fly    68 GVVEGPQKRFFEAEFLPKINHSSAGMLSLVSAGKNLVGSQFFLTLGENLTSLDGNHCVIGEVVEG 132
            |       :.|:.||.|.::|:..|:||:.::|.|...||||:|. .:...||..|.:.|.||.|
Human   347 G-------KPFKDEFRPNLSHTGRGILSMANSGPNSNRSQFFITF-RSCAYLDKKHTIFGRVVGG 403

  Fly   133 HEVLRKLNDAIVD-DSFRPYQDIRITHTVVLEDPFPNPRGLQAPSRSPSPSAERLKNGRIAADED 196
            .:||..:.:...| .:.||.::|||..|.|..||:                              
Human   404 FDVLTAMENVESDPKTDRPKEEIRIDATTVFVDPY------------------------------ 438

  Fly   197 IDDTDGMTAEEMQEML-AEREAKARATILEIVGDLPDADMAPPENVLF---VCK-LNPVTTD 253
             ::.|...|:|.:..| ...|.|.:::       .|.|....|:.  |   |.| :||..|:
Human   439 -EEADAQIAQERKTQLKVAPETKVKSS-------QPQAGSQGPQT--FRQGVGKYINPAATE 490

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5808NP_651291.1 cyclophilin_RRM 4..169 CDD:238902 61/165 (37%)
RRM <237..445 CDD:223796 7/21 (33%)
RRM_PPIL4 237..319 CDD:240681 7/21 (33%)
PPIL2XP_011528343.1 RING-Ubox_PPIL2 38..110 CDD:319577
RING_Ubox 100..159 CDD:388418
U-box domain, a modified RING finger 103..146 CDD:319361
cyclophilin_RING 281..440 CDD:238904 62/196 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0652
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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