DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5808 and Rbmy

DIOPT Version :9

Sequence 1:	NP_651291.1	Gene:	CG5808 / 42957	FlyBaseID:	FBgn0027617	Length:	653	Species:	Drosophila melanogaster
Sequence 2:	NP_001159856.1	Gene:	Rbmy / 19657	MGIID:	104732	Length:	380	Species:	Mus musculus

Alignment Length:	390	Identity:	87/390 - (22%)
Similarity:	143/390 - (36%)	Gaps:	106/390 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 LFVCKLNPVTTDDDLEIIFSSFGVLKGCEVIRDRKTGDSLQYAFVEFEDQKSCEAAYFKMDNVLI 306
            :|:..||..|....|:.||..||.:....::|||:|..|..:||:.|......:.|..:|:.|::
Mouse    10 IFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVIL 74

  Fly   307 DDRRIHV------------------DFSQS--VSKVTWRGKG------------RGIEGDYRKLD 339
            |.:||.|                  .||::  .|::...|:|            ..:.||....:
Mouse    75 DGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPN 139

  Fly   340 FNNLRDDKDHRKPNNGRSRTEDHKERNRTEDFRNRMSSAERRKAREQRHQEQSERDVRKNLQR-R 403
            ||.....:......|..|:.:|...:...       :||:.|.....|.:|...|::.:|:.| .
Mouse   140 FNVSSSGRHFAVKRNPSSKRDDPPSKRSA-------TSAQTRSNTGLRGREPHRREISRNMPRGE 197

  Fly   404 TRSKEKDEKSVYR-----SKKSQNESV------------RENS-------------NRERNRNEK 438
            ..|..:||..:.|     |...:.||.            ||.|             .|:|:.:|.
Mouse   198 PASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEY 262

  Fly   439 RSSRSRDATHRRYSRSRDREERRPSRPRDQLGRRSRSRDQKERR-----RSRPREQNERR-RSRS 497
            .|..|...|:|.|.|..:....|        |..:|..|....:     |..|...|... .|..
Mouse   263 LSGNSYRDTYRSYGRFHEAPSAR--------GGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSD 319

  Fly   498 RDQTGKR----PTQNRDRNDSRRFHSPQEGRRNDERSHRETSRNQRRSPERRQQSRNREDHRMDT 558
            .:::|::    |..:|:..|       :|||:  ||.|         ||:....|.:||.:..:|
Mouse   320 YERSGRQEVLPPPIDREYFD-------REGRQ--ERGH---------SPKDGLYSASRESYSSNT 366

Fly 559 558
Mouse 367 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5808	NP_651291.1	cyclophilin_RRM	4..169	CDD:238902
		RRM	<237..445	CDD:223796	59/265 (22%)
		RRM_PPIL4	237..319	CDD:240681	26/96 (27%)
Rbmy	NP_001159856.1	RRM_SF	7..86	CDD:302621	24/75 (32%)
		RRM	<9..>85	CDD:223796	24/74 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	82..226		27/150 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	279..358		21/104 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910