DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5808 and Ppib

DIOPT Version :9

Sequence 1:	NP_651291.1	Gene:	CG5808 / 42957	FlyBaseID:	FBgn0027617	Length:	653	Species:	Drosophila melanogaster
Sequence 2:	NP_035279.2	Gene:	Ppib / 19035	MGIID:	97750	Length:	216	Species:	Mus musculus

Alignment Length:	168	Identity:	59/168 - (35%)
Similarity:	89/168 - (52%)	Gaps:	17/168 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ETTMGDLTVDLFISERPIACLNFLKLCRLKY---YNFNLFHTVQQGFIAQTGD-PSGAGDGGSSI 66
            :.::|.:...||....|....||:.|...:.   |..:.||.|.:.|:.|.|| ..|.|.||.||
Mouse    54 DESVGRVVFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSI 118

  Fly    67 WGVVEGPQKRFFEAEFLPKINHSSAGMLSLVSAGKNLVGSQFFLTLGENLTS-LDGNHCVIGEVV 130
            :|      :||.:..|  |:.|...|.:|:.:|||:..|||||:|..:  || |||.|.|.|:|:
Mouse   119 YG------ERFPDENF--KLKHYGPGWVSMANAGKDTNGSQFFITTVK--TSWLDGKHVVFGKVL 173

  Fly   131 EGHEVLRKLNDAIVDDSFRPYQDIRITHT--VVLEDPF 166
            ||.:|:||:.....|...:|.:|:.|..:  :.:|.||
Mouse   174 EGMDVVRKVESTKTDSRDKPLKDVIIVDSGKIEVEKPF 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5808	NP_651291.1	cyclophilin_RRM	4..169	CDD:238902	59/168 (35%)
		RRM	<237..445	CDD:223796
		RRM_PPIL4	237..319	CDD:240681
Ppib	NP_035279.2	cyclophilin_ABH_like	45..203	CDD:238907	56/158 (35%)
Ppib	NP_035279.2	Prevents secretion from ER. /evidence=ECO:0000250	213..216
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900