DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5808 and cyn-4

DIOPT Version :9

Sequence 1:	NP_651291.1	Gene:	CG5808 / 42957	FlyBaseID:	FBgn0027617	Length:	653	Species:	Drosophila melanogaster
Sequence 2:	NP_496337.1	Gene:	cyn-4 / 174674	WormBaseID:	WBGene00000880	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	227	Identity:	73/227 - (32%)
Similarity:	104/227 - (45%)	Gaps:	30/227 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VVIETTMGDLTVDLFISERPIACLNFLKLCRLKYYNFNLFHTVQQGFIAQTGDPSGAGDGGSSIW 67
            |.:.|..|.|.::||..:.|.||.||:..|...|||...||.:.:.|:.|.|||:|.|.||.|||
Worm   282 VRLVTNFGPLNLELFAPKVPKACENFITHCSNGYYNNTKFHRLIKNFMLQGGDPTGTGHGGESIW 346

  Fly    68 GVVEGPQKRFFEAEFLPKINHSSAGMLSLVSAGKNLVGSQFFLTLGENLTSLDGNHCVIGEVVEG 132
               :.|    |..||:...:|.:.|:||:.:.|.|..|||||:|. .....||..|.:.|.:|.|
Worm   347 ---DKP----FSDEFISGFSHDARGVLSMANKGSNTNGSQFFITF-RPCKYLDRKHTIFGRLVGG 403

  Fly   133 HEVLRKLNDAIVDDSFR-PYQDIRITHTVVLEDPFPNPRGLQAPSRSPSPSAERLKNGRIAADED 196
            .:.|..:.....::... |...:.|....|..|||.     :|.....:..||.||.
Worm   404 QDTLTTIEKLETEEGTDVPMVSVVIMRAEVFVDPFE-----EAEKEVQAERAEILKK-------- 455

  Fly   197 IDDTDGMTAEEMQEMLAEREAKARATILEIVG 228
                   |:::... ||.::||..||..|.||
Worm   456 -------TSKDAAS-LANKKAKETATKPEAVG 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5808	NP_651291.1	cyclophilin_RRM	4..169	CDD:238902	57/165 (35%)
		RRM	<237..445	CDD:223796
		RRM_PPIL4	237..319	CDD:240681
cyn-4	NP_496337.1	Ubox	45..96	CDD:128780
cyn-4	NP_496337.1	cyclophilin_RING	281..440	CDD:238904	58/170 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810