Protein Alignment lili and LMBR1L

DIOPT Version :10

• Sequence 1: NP_651290.1
• Gene: lili / 42956
• FlyBaseID: FBgn0027539
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001339090.1
• Gene: LMBR1L / 55716
• HGNCID: 18268
• Length: 496
• Species: Homo sapiens
• Alignment Length: 518
• Identity: 217/518 - (41%)
• Similarity: 298/518 - (57%)
• Gaps: 61/518 - (11%)

  Fly     3 EEEEEEVTDLKLQLFHNTVREHIIFLLLIILLYSSSYVVVSRFRRRDRDDLYSNDEDEVLVYRIS 67
            |..:.||..::.||||..:||.||..||...||...::.::||::  ..:..:.|:::..|.:|:
Human     2 EAPDYEVLSVREQLFHERIRECIISTLLFATLYILCHIFLTRFKK--PAEFTTVDDEDATVNKIA 64

  Fly    68 FWLCTFTLAVAEGAAMLLPVSIASNEVLLLYPNSYYVKWLNSSLIQGLWNHVFLFSNLSLFIFLP 132
            ..|||||||:|.||.:|||.||.||||||..|.:||::|||.|||.||||.|||||||||...:|
Human    65 LELCTFTLAIALGAVLLLPFSIISNEVLLSLPRNYYIQWLNGSLIHGLWNLVFLFSNLSLIFLMP 129

  Fly   133 FVYLFSESTGFVGNKKGILPRVYETFTVFMLMAIIVLVLTAVLSAVF-----GIEKLQFFWFLNL 192
            |.|.|:||.||.|::||:|.|||||..:.||:.::||.:..|.||:.     ..|.|..||
Human   130 FAYFFTESEGFAGSRKGVLGRVYETVVMLMLLTLLVLGMVWVASAIVDKNKANRESLYDFW---- 190

  Fly   193 GSVHLPFLYSCVSFLGVMLMLICTPYGFVRLFGVVNQVLVRPMLLRDVNEEFSAFYMEEASVKRK 257
             ..:||:||||:|||||:|:|:|||.|..|:|.|..::||:|.||.|:.|:......|||::.|:
Human   191 -EYYLPYLYSCISFLGVLLLLVCTPLGLARMFSVTGKLLVKPRLLEDLEEQLYCSAFEEAALTRR 254

  Fly   258 LAHIELHNVSIADAANGGRLGNRIGLGRGRTFYPQPLLQHSQAHLYQRKAMASDVDELNDRLREL 322
            :.:                          .|....||                |::.|:.::..|
Human   255 ICN--------------------------PTSCWLPL----------------DMELLHRQVLAL 277

  Fly   323 DSERKELDKLRTSSTFQRTFVYPLAMLLLLFCTAVTILLVVQNTLELLIGIKALPLSTR----QF 383
            .::|..|:|.|.:|.:||...||||||.||..|.:::|:|..:.|||||...|:|...:    .:
Human   278 QTQRVLLEKRRKASAWQRNLGYPLAMLCLLVLTGLSVLIVAIHILELLIDEAAMPRGMQVVLILY 342

  Fly   384 ALGISSL---SKLGPFGAGLEVCLIFYLGATSVVGFYSMPFMRKVCPKRRQTSLPQLMLNCGFML 445
            ..|..||   ||...:.:.......|||..:|||||||.|..|.:.|:...|::.|::.||..:|
Human   343 PSGNPSLPLFSKPVSWDSRPSTSWTFYLMVSSVVGFYSSPLFRSLRPRWHDTAMTQIIGNCVCLL 407

  Fly   446 VLSSALPLLSRIIGITNFDLLGDFGAIEWLGNFQIVLLYNLVFGTTTALCLANKFTATVRREL 508
            |||||||:.||.:|:|.||||||||...|||||.||.|||..|...|.|||...|||.||.||
Human   408 VLSSALPVFSRTLGLTRFDLLGDFGRFNWLGNFYIVFLYNAAFAGLTTLCLVKTFTAAVRAEL 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lili	NP_651290.1	LMBR1	65..500	CDD:461429	191/446 (43%)
LMBR1L	NP_001339090.1	LMBR1	24..459	CDD:461429	200/483 (41%)