DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lili and lmbr1

DIOPT Version :9

Sequence 1:	NP_651290.1	Gene:	lili / 42956	FlyBaseID:	FBgn0027539	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001011160.1	Gene:	lmbr1 / 496578	XenbaseID:	XB-GENE-981846	Length:	485	Species:	Xenopus tropicalis

Alignment Length:	509	Identity:	216/509 - (42%)
Similarity:	308/509 - (60%)	Gaps:	58/509 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EEEEVTDLKLQLFHNTVREHIIFLLLIILLYSSSYVVVSRFRRRDRDDLYSNDEDEVLVYRISFW 69
            ||:||| ::.|.|::.|||.||..||..:||..||.::.|::|:..:    .::::..|.|:|.:
Frog     2 EEDEVT-IREQNFYSQVRECIICFLLFAILYIVSYFIIKRYKRKGDE----QEDEDATVNRVSLF 61

  Fly    70 LCTFTLAVAEGAAMLLPVSIASNEVLLLYPNSYYVKWLNSSLIQGLWNHVFLFSNLSLFIFLPFV 134
            ||||||||:.||.:|||.||.|||:||.:|.|||::|||.|||.||||.|.|||||.||:.:||.
Frog    62 LCTFTLAVSGGAVLLLPFSIISNEILLCFPKSYYIQWLNGSLIHGLWNLVSLFSNLCLFVLMPFA 126

  Fly   135 YLFSESTGFVGNKKGILPRVYETFTVFMLMAIIVLVLTAVLSAVF-----GIEKLQFFWFLNLGS 194
            :.|.||.||.|.||||..|:.||..:.:|:|:::..:..|.||:.     .:|.|...|     .
Frog   127 FFFLESEGFAGLKKGIKARILETIIMLILLALLIFGIVWVASALIDNSSASMESLYDLW-----D 186

  Fly   195 VHLPFLYSCVSFLGVMLMLICTPYGFVRLFGVVNQVLVRPMLLRDVNEEFSAFYMEEASVKRKLA 259
            .:||:||||:|.:|.:|:|:|||.|..|:|.|:.|:||:|.:|.|::|:.....::|.:::|||
Frog   187 CYLPYLYSCISLMGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDIDEQMYIISLQEEALQRKL- 250

  Fly   260 HIELHNVSIADAANGGRLGNRIGLGRGRTFYPQPLLQHSQAHLYQRKAMASDVDELNDRLRELDS 324
                         |||.             |...         |.||.:..|:  ||.|     |
Frog   251 -------------NGGN-------------YTAD---------YSRKKIEHDL--LNAR-----S 273

  Fly   325 ERKELDKLRTSSTFQRTFVYPLAMLLLLFCTAVTILLVVQNTLELLIGIKALPLSTRQFALGISS 389
            .:.:|::.:.:|.:||..|||..|:|||..|..:::||..|.|.||:...|:|..::....|.:|
Frog   274 MKSKLERRKNASAWQRNLVYPAVMILLLIATFSSVILVSLNILRLLVDETAMPKGSKGSGFGDAS 338

  Fly   390 LSKLGPFGAGLEVCLIFYLGATSVVGFYSMPFMRKVCPKRRQTSLPQLMLNCGFMLVLSSALPLL 454
            |...|..||.||:.|||||..:|||||||:.|.....|::..|::.:::.||..:||||||||::
Frog   339 LFTFGFAGATLEIILIFYLMVSSVVGFYSLRFFSSFTPRKDDTTMTKVIGNCLSILVLSSALPVM 403

  Fly   455 SRIIGITNFDLLGDFGAIEWLGNFQIVLLYNLVFGTTTALCLANKFTATVRREL 508
            ||.:|||.||||||||...|||||.||:.|||:|...|.|||..|||:.||.||
Frog   404 SRTLGITRFDLLGDFGRFNWLGNFYIVVAYNLMFAVMTTLCLVRKFTSAVREEL 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lili	NP_651290.1	LMBR1	63..495	CDD:282625	186/436 (43%)
lmbr1	NP_001011160.1	LMBR1	18..449	CDD:368121	201/482 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	401	1.000	Inparanoid score	I1877
OMA	1	1.010	-	-		QHG48055
OrthoDB	1	1.010	-	-		D334825at33208
OrthoFinder	1	1.000	-	-		FOG0003610
OrthoInspector	1	1.000	-	-		otm49025
Panther	1	1.100	-	-	O	PTHR12625
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2924
SonicParanoid	1	1.000	-	-		X2485
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.110