Protein Alignment lili and lmbr-1

DIOPT Version :10

• Sequence 1: NP_651290.1
• Gene: lili / 42956
• FlyBaseID: FBgn0027539
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001411903.1
• Gene: lmbr-1 / 176182
• WormBaseID: WBGene00019877
• Length: 739
• Species: Caenorhabditis elegans
• Alignment Length: 673
• Identity: 190/673 - (28%)
• Similarity: 304/673 - (45%)
• Gaps: 175/673 - (26%)

  Fly     2 DEEEE---EEVTDLKLQLFHNTVREHIIFLLLIILLYSSSYVVVSRFRRR-DRDDLYSNDEDEVL 62
            ||.||   :::.| |.:.|||.||:.||.:.|.:|||..:|.::||.:|: :|:.||:.:|| ..
 Worm    45 DEPEESYFQQMVD-KEKEFHNYVRQQIICMWLFMLLYLFAYWLISRLKRKTEREALYAGEED-YF 107

  Fly    63 VYRISFWLCTFTLAVAEGAAMLLPVSIASNEVLLLYPNSYYVKWLNSSLIQGLWNHVFLFSNLSL 127
            |||:|.|:.:...|.:.|:..|||.|:...|:|.||..:||::||:.|||..|||:||:.||:||
 Worm   108 VYRVSVWISSTATATSIGSLTLLPFSVIGVELLQLYDGNYYLQWLSYSLIGALWNYVFVLSNVSL 172

  Fly   128 FIFLPFVYLFSESTGF----VGNKKGILPRVYETFTVFMLMAIIVLVLTAVLSAVFGIEKLQFFW 188
            |:.|||.|.|.||.||    :||.:.:..|:||...:..|.|.::|.|..|:..:....    ..
 Worm   173 FVLLPFSYFFIESQGFSTSKIGNFQDMTQRIYEAMAISFLFAFVLLCLAEVVLTILDYP----VS 233

  Fly   189 FLNLGSVHLPFLYSCVSFLGVMLMLICTPYGFVRLFGVVNQVLVRPMLLRDVNEEFSAFYMEEAS 253
            ||::.||:||.:||||||:|.:|:||.|||||.::|.:....||... ..|:.||.|....:...
 Worm   234 FLSITSVNLPLIYSCVSFIGAVLLLISTPYGFAKMFSLARDFLVTEE-TADIEEENSEQSEDVTE 297

  Fly   254 VKRKLAHIELHNVSIADA---------------ANG----------------------------- 274
            .|...:...:|.|..:|.               |:|
 Worm   298 PKNSSSDETIHQVDRSDTPHLEDVVNDITENVDADGEFRKDSDSGIESGSTEEMRLNTDDEEMGI 362

  Fly   275 ------------GRLGN------------------------------------------------ 279
                        |.|||
 Worm   363 NDSDDKSAFGDDGDLGNSTPTKNKKKRRKHDYAATTPIVRKWDKDVPKKPKNPNFDYRNLKEYVK 427

  Fly   280 -----RIGLGRGRTF-YPQPLLQHSQAHLYQ------------------------------RKAM 308
                 |..|.....: :..|......|:.|.                              .:|.
 Worm   428 EARRQRSSLSESDDYWFGSPPRSSFSANYYSSRFSRWKHNSETGLNPSSSLLVDPFASGDFHEAS 492

  Fly   309 ASDVDE--LNDRLRELDSE---RKELDKLRTSSTFQR-------------TFVYPLAMLLLLFCT 355
            :|:...  |:...|....|   :..|..:::|..::|             :..:|:|...||..|
 Worm   493 SSEASSTPLSPARRTKSEEAIWKPVLHTVKSSKLYKRAIEKQGRLVKLFMSLRFPVAAAALLVLT 557

  Fly   356 AVTILLVVQNTLELLIGIKALPLSTRQFALGISSLSKLGPFGAGLEVCLIFYLGATSVVGFYSMP 420
            ..::::|..|||:||.|.::||:..:.  :.:.:....|.|||.:|..||.|:..||.||.||:|
 Worm   558 TCSLIMVATNTLKLLFGYRSLPVYAQY--IEVHTRHSFGLFGACIETLLIIYVMITSFVGLYSLP 620

  Fly   421 FMRKVCPKRRQTSLPQLMLNCGFMLVLSSALPLLSRIIGITNFDLLGDFGAIEWLGNFQIVLLYN 485
            .:|.:.|.|:.|.:|.:::|...:||::||||:....:|:|.|||||...:::|||:|::|:.||
 Worm   621 VLRSLRPVRKDTPMPTIIINSSIVLVVASALPVAVNTVGMTTFDLLGSHSSLQWLGSFRVVVAYN 685

  Fly   486 LVFGTTTALCLANKFTATVRREL 508
            .:|...:...|.|:.||::||::
 Worm   686 TLFVVLSVAFLFNQLTASMRRQI 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lili	NP_651290.1	LMBR1	65..500	CDD:461429	158/596 (27%)
lmbr-1	NP_001411903.1	LMBR1	68..698	CDD:461429	174/637 (27%)
		MDN1	<278..>381	CDD:444083	14/103 (14%)