DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6980 and Ttc4

DIOPT Version :9

Sequence 1:	NP_651289.1	Gene:	CG6980 / 42955	FlyBaseID:	FBgn0039228	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	XP_006503471.1	Gene:	Ttc4 / 72354	MGIID:	1919604	Length:	451	Species:	Mus musculus

Alignment Length:	194	Identity:	49/194 - (25%)
Similarity:	92/194 - (47%)	Gaps:	34/194 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 DVDKVRLKVKENRTVINRKSLEEDNEKQVKDMNQKSFMEQVEKDANDRAEARAKAEYEAELQRSQ 134
            :.||:.|.:|        |:..|.:.::..|:   :.::.:..| :||     ..|.:|:..:.:
Mouse    38 EFDKIPLFMK--------KAPSEIDPEEFPDL---ACLQSMIFD-DDR-----YPEEQAKTYKDE 85

  Fly   135 GNEAFRSQKYEKAILHYDKAI-IKVKD---SAITYCNRALCYIKLQNYKRALKDCQYVLEKLQES 195
            ||:.|:.:.|:||:|.|.:.: .|..|   :|:.|.|||.....|.|.:.:|.|. ...:||:..
Mouse    86 GNDYFKEKDYKKAVLSYSEGLKKKCADPDLNAVLYTNRAAAQYYLGNVRSSLNDV-LAAKKLKPG 149

  Fly   196 NLRAWLYQAHAYKGLKQDDKFEESV--------VKAREHNPKQL-AYIDKYIKQLEADLKALEI 250
            :|:|.:..|..:..||.   |.|:|        :.|:|....:: |..||..:..|.||:..::
Mouse   150 HLKAIIRGALCHLELKH---FAEAVNWCDEGLQIDAKEKKLLEIRAKADKLKRMEERDLRKAKL 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6980	NP_651289.1	TPR_11	127..190	CDD:290150	20/66 (30%)
		TPR repeat	128..156	CDD:276809	9/28 (32%)
		TPR repeat	161..192	CDD:276809	9/30 (30%)
		TPR_1	162..190	CDD:278916	9/27 (33%)
		TPR repeat	197..225	CDD:276809	9/35 (26%)
Ttc4	XP_006503471.1	3a0801s09	73..>218	CDD:273380	40/147 (27%)
		TPR repeat	79..107	CDD:276809	9/27 (33%)
		TPR repeat	116..146	CDD:276809	9/30 (30%)
		TPR repeat	151..179	CDD:276809	8/30 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R218
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940