DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6980 and Ttc9

DIOPT Version :9

Sequence 1:	NP_651289.1	Gene:	CG6980 / 42955	FlyBaseID:	FBgn0039228	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001028321.1	Gene:	Ttc9 / 69480	MGIID:	1916730	Length:	219	Species:	Mus musculus

Alignment Length:	175	Identity:	45/175 - (25%)
Similarity:	71/175 - (40%)	Gaps:	46/175 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 ANDRAEARAKAEYEAELQR------SQGNEAFRSQKYEKAILHYDKAIIKVKD------------ 160
            |.:|.:|...|| .|||.|      |||.:.::.:|:.:||..|.:|::::|.
Mouse    37 APERGQAGTAAE-PAELIRRAHEFKSQGAQCYKDKKFREAIGKYHRALLELKGLLPSQEERDARP 100

  Fly   161 --------------------SAI---TYCNRALCYI--KLQNYKRALKDCQYVLEKLQESNLRAW 200
                                .||   .|.:.|.|.:  :|.||:|..:.|..||:| :..|.:|.
Mouse   101 ASSAGVPKSSRLSEEQSKTVEAIEIDCYNSLAACLLQAELVNYERVKEYCLKVLKK-EGENFKAL 164

  Fly   201 LYQAHAYKGLKQDDKFEESVVKAREHNPKQLAYIDKYIKQLEADL 245
            .....|:..|...||....:.:||...|.....| :||:..|..|
Mouse   165 YRSGVAFYHLGDYDKALYYLKEARTRQPTDTNVI-RYIQLTEMKL 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6980	NP_651289.1	TPR_11	127..190	CDD:290150	24/105 (23%)
		TPR repeat	128..156	CDD:276809	12/33 (36%)
		TPR repeat	161..192	CDD:276809	12/35 (34%)
		TPR_1	162..190	CDD:278916	11/32 (34%)
		TPR repeat	197..225	CDD:276809	6/27 (22%)
Ttc9	NP_001028321.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49		5/12 (42%)
		TPR 1	56..89		9/32 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	94..115		0/20 (0%)
		TPR_11	124..192	CDD:290150	19/68 (28%)
		TPR 2	125..160		11/35 (31%)
		TPR repeat	127..156	CDD:276809	10/28 (36%)
		TPR 3	161..194		8/32 (25%)
		TPR repeat	161..187	CDD:276809	5/25 (20%)
		TPR_1	162..194	CDD:278916	8/31 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960