DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6980 and TTC31

DIOPT Version :9

Sequence 1:	NP_651289.1	Gene:	CG6980 / 42955	FlyBaseID:	FBgn0039228	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	XP_011531337.1	Gene:	TTC31 / 64427	HGNCID:	25759	Length:	539	Species:	Homo sapiens

Alignment Length:	104	Identity:	27/104 - (25%)
Similarity:	48/104 - (46%)	Gaps:	11/104 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 AELQRSQ-----GNEAFRSQKYEKAILHYDKAI-IKVKDSAITYCNRALCYIKLQNYKRALKDCQ 186
            |.||:||     |....::..|.:|::.:.:|: :..:|..: :.||:.|:.:|.....||.|.|
Human   320 AALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRL-FGNRSFCHERLGQPAWALADAQ 383

  Fly   187 YVLEKLQESNLRAWLYQAHAYKGLKQDDKFEESVVKARE 225
            ..| .|:....|.......|..||:   :|.|:....:|
Human   384 VAL-TLRPGWPRGLFRLGKALMGLQ---RFREAAAVFQE 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6980	NP_651289.1	TPR_11	127..190	CDD:290150	18/67 (27%)
		TPR repeat	128..156	CDD:276809	9/33 (27%)
		TPR repeat	161..192	CDD:276809	9/30 (30%)
		TPR_1	162..190	CDD:278916	8/27 (30%)
		TPR repeat	197..225	CDD:276809	6/27 (22%)
TTC31	XP_011531337.1	TPR_11	324..390	CDD:290150	17/67 (25%)
		TPR repeat	325..353	CDD:276809	6/27 (22%)
		TPR repeat	358..388	CDD:276809	10/31 (32%)
		TPR repeat	393..421	CDD:276809	7/29 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0548
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810