DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6980 and CG34274

DIOPT Version :9

Sequence 1:	NP_651289.1	Gene:	CG6980 / 42955	FlyBaseID:	FBgn0039228	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001097807.1	Gene:	CG34274 / 5740212	FlyBaseID:	FBgn0085303	Length:	250	Species:	Drosophila melanogaster

Alignment Length:	222	Identity:	72/222 - (32%)
Similarity:	115/222 - (51%)	Gaps:	18/222 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 PSVADDFAEFEATLAKIDCILQNKAPCDDEDSKAGGDAKEKINFDNLDVDKVRLKVKENRTVINR 87
            |:..:|..|:      :| :|:|....|....:    .|..|..|::..      :...|:.::.
  Fly    44 PTKVEDVIEY------LD-VLENANKTDSSKKR----QKSTITMDDIKC------IVTRRSAVST 91

  Fly    88 KSLEEDNEKQ-VKDMNQKSFMEQVEKDANDRAEARAKAEYEAELQRSQGNEAFRSQKYEKAILHY 151
            .:......|: :.:.||.:||.|::.:.:||..||.:.|..||..|..||..:|...:..|..:|
  Fly    92 TTFRRGKAKRALINTNQFTFMRQIDSEPDDRVLAREQREDVAETFRRMGNYEYRKLNFSLAKDYY 156

  Fly   152 DKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEKLQESNLRAWLYQAHAYKGLKQDDKF 216
            .|.|..:|||.:.|.|||||:|||:.:|..:.||.|||.|:.|..||||||:|.|||.|..:..|
  Fly   157 SKGIQYIKDSPVLYVNRALCFIKLREFKLGIIDCDYVLAKIDEHYLRAWLYRAAAYKRLNDEPNF 221

  Fly   217 EESVVKAREHNPKQLAYIDKYIKQLEA 243
            |.||.:||..|.....:||:::.::.:
  Fly   222 EYSVDRARRFNRSDADFIDEFLDKMRS 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6980	NP_651289.1	TPR_11	127..190	CDD:290150	27/62 (44%)
		TPR repeat	128..156	CDD:276809	9/27 (33%)
		TPR repeat	161..192	CDD:276809	16/30 (53%)
		TPR_1	162..190	CDD:278916	14/27 (52%)
		TPR repeat	197..225	CDD:276809	16/27 (59%)
CG34274	NP_001097807.1	TPR_11	133..195	CDD:290150	27/61 (44%)
		TPR repeat	133..161	CDD:276809	9/27 (33%)
		TPR repeat	166..197	CDD:276809	16/30 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449143
Domainoid	1	1.000	44	1.000	Domainoid score	I4681
eggNOG	1	0.900	-	-		E2759_KOG0548
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005389
OrthoInspector	1	1.000	-	-		otm26027
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.740