DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6980 and si:dkey-33c12.4

DIOPT Version :9

Sequence 1:	NP_651289.1	Gene:	CG6980 / 42955	FlyBaseID:	FBgn0039228	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	XP_021336269.1	Gene:	si:dkey-33c12.4 / 560112	ZFINID:	ZDB-GENE-030131-2527	Length:	648	Species:	Danio rerio

Alignment Length:	263	Identity:	54/263 - (20%)
Similarity:	100/263 - (38%)	Gaps:	49/263 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DNAQLKATMLNCNLNPSVADDFAEFEATLAKIDCILQNKAPCDDEDSKAGGDAKEKINFDNLDVD 72
            :|...|.....|:   ||..|.....|.::..|      :..|:||.|....|.|.   :.||::
Zfish   195 ENKDKKCKNKGCS---SVPPDPQPISAPVSSSD------SSSDEEDDKKEDSAIEP---EELDMN 247

  Fly    73 KVRLKVKENRTVINRKSLEED----------NEKQVKDMNQKSFMEQVEKDANDRAEARAKAEYE 127
            ...:   .|...|.::.||:.          |.|:..:..||:.:...::.|.:...........
Zfish   248 SCFV---SNAAAIAKRKLEQKPKPDKKPAQANPKKQHESQQKATVMPQKQVAKEEVNGEESVNAN 309

  Fly   128 AELQRSQ-----GNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQY 187
            ..:.||.     |||...|...|.|:.::..||.........:.||:.||.|:..|:::|.|.:.
Zfish   310 DFITRSVELAVIGNEYAGSGNMEMAVKYFTDAIKHNPKEYKLFGNRSYCYEKMLQYEKSLTDAEI 374

  Fly   188 VLEKLQESNLRAWLYQAHAYKGLKQDDKFEESVVKAREHNPKQLAY-----IDKYIKQLEADLKA 247
            .|     |....|:      |||.:..:   ::|..:.:|..:|.:     :|...|....::..
Zfish   375 AL-----SMNPKWI------KGLYRKGR---ALVGLKRYNEARLTFGEVLKLDSSCKDAAEEIMR 425

  Fly   248 LEI 250
            :::
Zfish   426 VQL 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6980	NP_651289.1	TPR_11	127..190	CDD:290150	18/67 (27%)
		TPR repeat	128..156	CDD:276809	9/32 (28%)
		TPR repeat	161..192	CDD:276809	9/30 (30%)
		TPR_1	162..190	CDD:278916	8/27 (30%)
		TPR repeat	197..225	CDD:276809	5/27 (19%)
si:dkey-33c12.4	XP_021336269.1	PLN03088	258..>439	CDD:330826	36/185 (19%)
		TPR repeat	348..378	CDD:276809	9/34 (26%)
		TPR repeat	383..411	CDD:276809	6/36 (17%)
		UBA	430..456	CDD:270456
		RRM	<471..>614	CDD:223796
		RRM	519..584	CDD:214636
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0548
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900