DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6980 and stip1

DIOPT Version :9

Sequence 1:	NP_651289.1	Gene:	CG6980 / 42955	FlyBaseID:	FBgn0039228	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_989360.1	Gene:	stip1 / 394990	XenbaseID:	XB-GENE-958361	Length:	543	Species:	Xenopus tropicalis

Alignment Length:	196	Identity:	51/196 - (26%)
Similarity:	90/196 - (45%)	Gaps:	34/196 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 KVKENRTVIN--RKSLEEDNEKQVKDMNQKSFMEQVEKDANDRAEARAKAEYEAELQRSQGNEAF 139
            |.::|:..|:  .|||.|....:|....|::  |::.|:....|........|   ::|:|||:|
Frog   312 KEEKNKEAIHFFNKSLAEHRTPEVLKKCQQA--EKILKEQERLAYINPDLALE---EKSKGNESF 371

  Fly   140 RSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEKLQESNLRAWLYQA 204
            :...|.:|:.||.:||.:..:.|..|.|||.||.||..::.|||||:..: :|:...::.:..:|
Frog   372 QKGDYPQAMKHYTEAIKRNPNDAKLYSNRAACYTKLLEFQLALKDCEECI-RLEPKFIKGYTRKA 435

  Fly   205 HAYKGLKQDDKFEESVVKARE--------------------------HNPKQLAYIDKYIKQLEA 243
            .|.:.:|...|..:...||.|                          .:.|:.|..|..::|:.:
Frog   436 AALEAMKDYSKAMDVYQKAMELDSTCKEATDGYQRCMMSQYHRNDSPEDVKRRAMADPEVQQIMS 500

  Fly   244 D 244
            |
Frog   501 D 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6980	NP_651289.1	TPR_11	127..190	CDD:290150	26/62 (42%)
		TPR repeat	128..156	CDD:276809	10/27 (37%)
		TPR repeat	161..192	CDD:276809	14/30 (47%)
		TPR_1	162..190	CDD:278916	14/27 (52%)
		TPR repeat	197..225	CDD:276809	6/27 (22%)
stip1	NP_989360.1	3a0801s09	<2..532	CDD:273380	51/196 (26%)
		TPR repeat	4..32	CDD:276809
		TPR repeat	37..67	CDD:276809
		TPR repeat	72..100	CDD:276809
		TPR repeat	225..253	CDD:276809
		TPR repeat	258..288	CDD:276809
		TPR repeat	300..328	CDD:276809	5/15 (33%)
		TPR repeat	364..388	CDD:276809	10/23 (43%)
		TPR repeat	393..423	CDD:276809	14/30 (47%)
		TPR repeat	428..456	CDD:276809	6/27 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000