DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6980 and Dpit47

DIOPT Version :9

Sequence 1:	NP_651289.1	Gene:	CG6980 / 42955	FlyBaseID:	FBgn0039228	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001260729.1	Gene:	Dpit47 / 35565	FlyBaseID:	FBgn0266518	Length:	396	Species:	Drosophila melanogaster

Alignment Length:	183	Identity:	40/183 - (21%)
Similarity:	78/183 - (42%)	Gaps:	24/183 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 INRKSLEE--DNEKQVKDMNQKSFM----EQVEKDANDRAEARAKAEYEAELQ---------RSQ 134
            :.:|..||  ..::..::|::..|.    .|...|.:...|...|.:|:.|..         :..
  Fly    33 LEKKRYEEGWPEDRWQEEMDKHPFFMKRAPQPGDDVHPMFEGLQKLKYDPEENTRDELALNYKED 97

  Fly   135 GNEAFRSQKYEKAILHYDKAIIKVKDS----AITYCNRALCYIKLQNYKRALKDCQYVLEKLQES 195
            ||...:.:|:..||..:.:.|....|:    |:.|.||:..:..::||:.:|.|.|..|....:.
  Fly    98 GNFYMKHKKFRMAIYSFTEGIKTKTDNPDVLAVLYNNRSAAHFFIKNYRSSLSDAQRALFYKPDY 162

  Fly   196 NLRAWLYQAHAYKGLKQDD---KFEESVVKAREHNPKQLAYIDK-YIKQLEAD 244
            ....|.....||: |::.|   :..|.:::....|...:|.:.| .:|:||.:
  Fly   163 TKARWRSAQCAYE-LERFDLCTQMCEELLEVDVDNEVAIALLHKNKMKKLEIE 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6980	NP_651289.1	TPR_11	127..190	CDD:290150	17/75 (23%)
		TPR repeat	128..156	CDD:276809	6/36 (17%)
		TPR repeat	161..192	CDD:276809	10/34 (29%)
		TPR_1	162..190	CDD:278916	9/27 (33%)
		TPR repeat	197..225	CDD:276809	6/30 (20%)
Dpit47	NP_001260729.1	3a0801s09	84..>179	CDD:273380	21/95 (22%)
		TPR repeat	91..119	CDD:276809	5/27 (19%)
		TPR repeat	124..158	CDD:276809	10/33 (30%)
		TPR repeat	163..191	CDD:276809	6/28 (21%)
		TPR repeat	197..227	CDD:276809	5/18 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R218
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.940