DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6980 and Stip1

DIOPT Version :9

Sequence 1:NP_651289.1 Gene:CG6980 / 42955 FlyBaseID:FBgn0039228 Length:250 Species:Drosophila melanogaster
Sequence 2:NP_058017.1 Gene:Stip1 / 20867 MGIID:109130 Length:543 Species:Mus musculus


Alignment Length:276 Identity:60/276 - (21%)
Similarity:106/276 - (38%) Gaps:84/276 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    52 EDSKAGGDAKEKINFDNL--------DVDKVRLKVKENRTVIN-------------RKSLE---- 91
            ::.:.|.||.:|.:||..        ::|...:....|:..::             .|::|    
Mouse   227 KEKELGNDAYKKKDFDKALKHYDRAKELDPTNMTYITNQAAVHFEKGDYNKCRELCEKAIEVGRE 291

  Fly    92 --ED----------------NEKQVKD---MNQKSFMEQVEKDANDRAEARAKAEYEAEL----- 130
              ||                .|::.||   ...||..|....|...:.:...|...|.|.     
Mouse   292 NREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYIN 356

  Fly   131 ------QRSQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVL 189
                  ::::|||.|:...|.:|:.||.:||.:....|..|.|||.||.||..::.|||||:..:
Mouse   357 PDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPRDAKLYSNRAACYTKLLEFQLALKDCEECI 421

  Fly   190 EKLQESNLRAWLYQAHAYKGLKQDDKFEESVVKA-----------------------REHNP--- 228
            : |:.:.::.:..:|.|.:.:|...|..:...||                       |..:|   
Mouse   422 Q-LEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQRCMMAQYNRHDSPEDV 485

  Fly   229 KQLAYIDKYIKQLEAD 244
            |:.|..|..::|:.:|
Mouse   486 KRRAMADPEVQQIMSD 501

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6980NP_651289.1 TPR_11 127..190 CDD:290150 26/73 (36%)
TPR repeat 128..156 CDD:276809 10/38 (26%)
TPR repeat 161..192 CDD:276809 14/30 (47%)
TPR_1 162..190 CDD:278916 14/27 (52%)
TPR repeat 197..225 CDD:276809 6/50 (12%)
Stip1NP_058017.1 TPR 1 4..37
TPR_11 6..69 CDD:290150
TPR 7..37 CDD:197478
TPR repeat 7..32 CDD:276809
TPR repeat 37..67 CDD:276809
TPR 2 39..71
TPR_11 40..100 CDD:290150
TPR repeat 72..100 CDD:276809
TPR 3 73..105
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 191..233 0/5 (0%)
Bipartite nuclear localization signal. /evidence=ECO:0000255 222..239 3/11 (27%)
TPR_11 224..287 CDD:290150 9/59 (15%)
TPR 4 225..258 7/30 (23%)
TPR repeat 229..253 CDD:276809 6/23 (26%)
TPR_1 231..258 CDD:278916 7/26 (27%)
TPR_12 255..328 CDD:290160 11/72 (15%)
TPR repeat 258..288 CDD:276809 2/29 (7%)
TPR 5 260..292 3/31 (10%)
TPR 6 300..333 6/32 (19%)
TPR 300..328 CDD:197478 5/27 (19%)
TPR repeat 300..328 CDD:276809 5/27 (19%)
TPR_11 360..425 CDD:290150 25/65 (38%)
TPR 7 360..393 10/32 (31%)
TPR_1 364..393 CDD:278916 10/28 (36%)
TPR repeat 364..388 CDD:276809 9/23 (39%)
TPR_11 393..458 CDD:290150 21/65 (32%)
TPR repeat 393..423 CDD:276809 14/30 (47%)
TPR_1 394..427 CDD:278916 15/33 (45%)
TPR 8 395..427 14/32 (44%)
TPR 9 428..461 6/32 (19%)
TPR repeat 428..456 CDD:276809 6/27 (22%)
STI1 492..531 CDD:128966 3/10 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0548
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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