DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6980 and sti-1

DIOPT Version :9

Sequence 1:	NP_651289.1	Gene:	CG6980 / 42955	FlyBaseID:	FBgn0039228	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001367444.1	Gene:	sti-1 / 178587	WormBaseID:	WBGene00019983	Length:	320	Species:	Caenorhabditis elegans

Alignment Length:	209	Identity:	50/209 - (23%)
Similarity:	95/209 - (45%)	Gaps:	39/209 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 GDAKEKINFDNLDVDKVRLKVKENRTVINRKSLEEDNEKQVKDMNQKSFMEQVEKDANDRAEARA 122
            |:|.:|.|..:|.|......:.|.|        :.:..|:||::.::  ::..|:.|....|.
Worm    87 GNAFQKQNDLSLAVQWFHRSLSEFR--------DPELVKKVKELEKQ--LKAAERLAYINPEL-- 139

  Fly   123 KAEYEAELQRSQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQ- 186
                 |:.::::|||.|:...|..|:.||::|:.:..::||.|.|||.|..||..::|||.||.
Worm   140 -----AQEEKNKGNEYFKKGDYPTAMRHYNEAVKRDPENAILYSNRAACLTKLMEFQRALDDCDT 199

  Fly   187 -----------YVLEKLQESNLRAWLYQAHAYKGLKQDDKFEE-------SVVKAREHNP---KQ 230
                       |:.:......:|.|.....||:...|.|...|       :.:::.:.:|   |:
Worm   200 CIRLDSKFIKGYIRKAACLVAMREWSKAQRAYEDALQVDPSNEEAREGVRNCLRSNDEDPEKAKE 264

  Fly   231 LAYIDKYIKQLEAD 244
            .:..|..::::..|
Worm   265 RSLADPEVQEILRD 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6980	NP_651289.1	TPR_11	127..190	CDD:290150	25/74 (34%)
		TPR repeat	128..156	CDD:276809	10/27 (37%)
		TPR repeat	161..192	CDD:276809	15/42 (36%)
		TPR_1	162..190	CDD:278916	15/39 (38%)
		TPR repeat	197..225	CDD:276809	7/34 (21%)
sti-1	NP_001367444.1	3a0801s09	<5..>241	CDD:273380	45/170 (26%)
		TPR repeat	5..33	CDD:276809
		TPR repeat	38..68	CDD:276809
		TPR repeat	80..108	CDD:276809	6/20 (30%)
		TPR repeat	140..168	CDD:276809	10/27 (37%)
		TPR repeat	173..203	CDD:276809	14/29 (48%)
		TPR repeat	208..236	CDD:276809	5/27 (19%)
		STI1	259..311	CDD:407696	4/20 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0548
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810