DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ets96B and ets2

DIOPT Version :9

Sequence 1:	NP_996290.1	Gene:	Ets96B / 42952	FlyBaseID:	FBgn0039225	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001018874.1	Gene:	ets2 / 326672	ZFINID:	ZDB-GENE-050522-552	Length:	439	Species:	Danio rerio

Alignment Length:	322	Identity:	92/322 - (28%)
Similarity:	126/322 - (39%)	Gaps:	100/322 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 PHPHPYCYR--FPSSPPAGILKKSDEEATSAAVYCSDVSSGQHFPHHTKIEHADSTTTAAQQQQQ 328
            |:||....|  |.:|..|.:|..:.|....|....|.||  ..:..|...::.....||....:|
Zfish   188 PNPHSSLLRELFQTSDDAALLASAAELPACAKPQLSTVS--VRYRSHEFTKNTPQLRTAGSSGEQ 250

  Fly   329 QQEQQQQQQQQQQQQQHQQQLQQAAALHPHHHHSHHGHHGHQQAEQQALTHLTPL----HAASAF 389
            ..::..:..::             ..|.....||.........:.......|.||    |..| |
Zfish   251 ASQESVESAEE-------------CVLRSWGSHSSLADTQRVPSYDSFEEELLPLGLQKHGRS-F 301

  Fly   390 KFSHTAVISSSAVYATPSHYAHQQQTQSQSVYRDLSPTTLAAVSDADLKYDSGPYNAAISSTYPS 454
            |                 .|. |::.|:|...|.:.|..:.|
Zfish   302 K-----------------DYV-QERNQTQETGRPVIPAAVLA----------------------- 325

  Fly   455 ALRPNVVDSTTSSDAELRLDQFYASNGISTSSNGQAISQRRGSLQLWQFLVALLDEPTTSASCIA 519
                                      |.:.|          |.:||||||:.||.: :|..|.|:
Zfish   326 --------------------------GFTGS----------GPIQLWQFLLELLTD-STCQSIIS 353

  Fly   520 WTGRGMEFKLIEPEEVARRWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVNGERYVYRFVCD 581
            |||.|.||||.:|:|||||||.:||:|.|||:||||.|||||:|.|:.|.:|:|||||||||
Zfish   354 WTGDGWEFKLTDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTSGKRYVYRFVCD 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ets96B	NP_996290.1	ETS	497..583	CDD:197710	55/85 (65%)
ets2	NP_001018874.1	SAM_superfamily	76..164	CDD:301707
ets2	NP_001018874.1	ETS	332..416	CDD:197710	55/85 (65%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243757at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920