DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ets96B and Elk1

DIOPT Version :9

Sequence 1:	NP_996290.1	Gene:	Ets96B / 42952	FlyBaseID:	FBgn0039225	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001101529.1	Gene:	Elk1 / 314436	RGDID:	1598663	Length:	427	Species:	Rattus norvegicus

Alignment Length:	137	Identity:	62/137 - (45%)
Similarity:	85/137 - (62%)	Gaps:	11/137 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   497 SLQLWQFLVALLDEPTTSASCIAWTGR-GMEFKLIEPEEVARRWGLQKNRPAMNYDKLSRSLRYY 560
            |:.|||||:.||.| ..:...|:||.| |.||||::.|||||.|||:||:..||||||||:||||
  Rat     4 SVTLWQFLLQLLRE-QGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKLSRALRYY 67

  Fly   561 YEKGIMQKVNGERYVYRFVCDPDALFNMAYGHLTTGSGKGDQHQLTLSLAKTPPT----SGDSQT 621
            |:|.|::||:|:::||:||..|:..     |..|.......:..:|.::|..|.|    .||:.|
  Rat    68 YDKNIIRKVSGQKFVYKFVSYPEVA-----GCSTEDCPPQPEVSVTSAVAMAPATVHSGPGDNAT 127

  Fly   622 QSPRVAK 628
            ..|...|
  Rat   128 GKPGTPK 134

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ets96B	NP_996290.1	ETS	497..583	CDD:197710	50/86 (58%)
Elk1	NP_001101529.1	ETS	4..89	CDD:197710	50/85 (59%)
		PHA03247	<100..427	CDD:223021	9/35 (26%)
		PHA03132	112..>246	CDD:222997	8/23 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..146		6/19 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	166..202
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	226..252
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	300..350
		Sufficient for interaction with MAD2L2. /evidence=ECO:0000250\|UniProtKB:P19419	348..398
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X7531
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810