DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ets96B and Etv3

DIOPT Version :9

Sequence 1:	NP_996290.1	Gene:	Ets96B / 42952	FlyBaseID:	FBgn0039225	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001076787.1	Gene:	Etv3 / 27049	MGIID:	1350926	Length:	513	Species:	Mus musculus

Alignment Length:	168	Identity:	57/168 - (33%)
Similarity:	79/168 - (47%)	Gaps:	32/168 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   498 LQLWQFLVALLDEPTTSASCIAW-TGRGMEFKLIEPEEVARRWGLQKNRPAMNYDKLSRSLRYYY 561
            :|||.|::.|| :.......||| .|...||.:.:|:||||.||.:|.:|.||||||||:|||||
Mouse    35 IQLWHFILELL-QKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYY 98

  Fly   562 EKGIMQKVNGERYVYRFVCD-------------------------PDALFNMAYGHLTTGSGKGD 601
            .|.|:.|..|:|:.|:|..:                         |.|.....:..|.:.|..||
Mouse    99 NKRILHKTKGKRFTYKFNFNKLVMPNYPFINIRSSGVVPQSAPPVPTASSRFHFPPLDSHSPTGD 163

  Fly   602 QHQ---LTLSLAKTPPTSGDSQTQSPRVAKSEYYDTAA 636
            ...   ...||:.:.|.||  .|...:|..|:..|.:|
Mouse   164 VQPGRFSASSLSASGPESG--VTTDRKVEPSDLEDGSA 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ets96B	NP_996290.1	ETS	497..583	CDD:197710	41/110 (37%)
Etv3	NP_001076787.1	ETS	34..120	CDD:197710	41/85 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	138..202		16/64 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	333..513
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810