Protein Alignment Ets96B and ERG

DIOPT Version :10

• Sequence 1: NP_996290.1
• Gene: Ets96B / 42952
• FlyBaseID: FBgn0039225
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001129626.1
• Gene: ERG / 2078
• HGNCID: 3446
• Length: 486
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 84/281 - (29%)
• Similarity: 124/281 - (44%)
• Gaps: 90/281 - (32%)

  Fly   361 HSHHGHHGHQQAEQQALTHLTP-------------LHA----ASAFKFSHTAVISSSAVYATPSH 408
            |.|:       ..:..|.|||.             :||    .:||.|.:|
Human   198 HLHY-------LRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNT-------------- 241

  Fly   409 YAHQQQTQSQSVYRDLSPTTLAAVSDADLKYDSGPYNAAISSTYPS----ALRPNVVDSTTSSDA 469
                      |||.:   .|....:..||.|:....:|.....:|:    |.:|:......:.|.
Human   242 ----------SVYPE---ATQRITTRPDLPYEPPRRSAWTGHGHPTPQSKAAQPSPSTVPKTEDQ 293

  Fly   470 ELRLDQFY----ASNGISTSSNGQAISQRRGSLQLWQFLVALLDEPTTSASCIAWTGRGMEFKLI 530
            ..:||.:.    .|:.::...:||        :||||||:.||.: ::::|||.|.|...|||:.
Human   294 RPQLDPYQILGPTSSRLANPGSGQ--------IQLWQFLLELLSD-SSNSSCITWEGTNGEFKMT 349

  Fly   531 EPEEVARRWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVNGERYVYRFVCDPDALFNMAYGHLTT 595
            :|:|||||||.:|::|.||||||||:|||||:|.||.||:|:||.|:|
Human   350 DPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF----------------- 397

  Fly   596 GSGKGDQHQLTLSLAKTPPTS 616
                 |.|.:..:|...||.|
Human   398 -----DFHGIAQALQPHPPES 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ets96B	NP_996290.1	ETS	497..583	CDD:197710	49/85 (58%)
ERG	NP_001129626.1	SAM_PNT-ERG	134..208	CDD:176090	2/16 (13%)
		ETS	317..400	CDD:197710	51/113 (45%)