DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ets96B and Gabpa

DIOPT Version :9

Sequence 1:	NP_996290.1	Gene:	Ets96B / 42952	FlyBaseID:	FBgn0039225	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_006522968.1	Gene:	Gabpa / 14390	MGIID:	95610	Length:	456	Species:	Mus musculus

Alignment Length:	147	Identity:	60/147 - (40%)
Similarity:	86/147 - (58%)	Gaps:	3/147 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   448 ISSTYPSALRPNVVDSTTSSDAELRLDQFYASNGISTSSNGQAIS-QRRGSLQLWQFLVALLDEP 511
            |.::.|.| .|..:....||....::.:....:|...||.|.... ...|.:||||||:.||.:
Mouse   272 IPASVPPA-TPTTIKVINSSAKAAKVQRSPRISGEDRSSPGNRTDLGNNGQIQLWQFLLELLTD- 334

  Fly   512 TTSASCIAWTGRGMEFKLIEPEEVARRWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVNGERYVY 576
            ..:..||:|.|...||||.:||.||::||.:||:|.|||:||||:|||||:..::.||.|:|:||
Mouse   335 KDARDCISWVGDEGEFKLNQPELVAQKWGQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVY 399

  Fly   577 RFVCDPDALFNMAYGHL 593
            :||||...|...:...|
Mouse   400 KFVCDLKTLIGYSAAEL 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ets96B	NP_996290.1	ETS	497..583	CDD:197710	47/85 (55%)
Gabpa	XP_006522968.1	GABP-alpha	40..119	CDD:371630
		SAM_PNT-GABP-alpha	168..254	CDD:176084
		ETS	321..405	CDD:197710	46/84 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243757at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820