DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5805 and slc25a44b

DIOPT Version :9

Sequence 1:	NP_001287513.1	Gene:	CG5805 / 42950	FlyBaseID:	FBgn0039223	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001013537.1	Gene:	slc25a44b / 541392	ZFINID:	ZDB-GENE-050320-89	Length:	316	Species:	Danio rerio

Alignment Length:	322	Identity:	125/322 - (38%)
Similarity:	193/322 - (59%)	Gaps:	23/322 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 IRTIEWDMMNKTKFFPLSMLSSFSVRCCLFPLTVIKTQLQVQHKSDVYKGMVDCAMKIYRSEGVP 93
            |:.|||:.::|.||:...:..:.::|..::|.|:|:|:||||....:|.|..|...||.|:||:.
Zfish     7 IQIIEWEDLDKRKFYSFGLFMTMTIRATVYPATLIRTRLQVQKGKSLYTGTYDAFRKILRTEGLR 71

  Fly    94 GLYRGFWISSVQIVSGVFYISTYEGVRHVLNDLGAGHRMKALAGGGCASLVGQTIIVPFDVISQH 158
            ||||||.:::..::||..||:|||.||..::.....:.:|:|..||.||||.|:|.||.||:||.
Zfish    72 GLYRGFMVTTFTLISGQAYITTYELVRKYVSSYSKDNTLKSLVAGGSASLVAQSITVPIDVVSQQ 136

  Fly   159 AMVLGMSAH-----------AGSKGDINPLGIKSWPGRSRLHISMDIGREIMRRDGFRGFYRGYT 212
            .|:.|...|           :|:|..:       :.|::|     ||..:|...||.|||||||.
Zfish   137 LMMQGQGEHLTRFKVKPKTPSGAKHSV-------FSGQTR-----DIIGQIFAADGIRGFYRGYV 189

  Fly   213 ASLMAYVPNSAMWWAFYHLYQDELFRICPVWVSHLFIQCVAGSLGGFTTTILTNPLDIVRARLQV 277
            |||:.|:||||:||.|||.|.::|.::.|....||.:|.:||.|...|.:.:|||:|::|||:||
Zfish   190 ASLLTYIPNSAVWWPFYHFYAEQLSKMAPSNCPHLVLQAMAGPLAAATASTVTNPMDVIRARVQV 254

  Fly   278 HRLDSMSVAFRELWQEEKLNCFFKGLSARLVQSAAFSFSIILGYETIKRIAVDEQYKHQIRW 339
            ....|:...|.:|.:||......||||||::.||..:..:::||||:|::::..:......|
Zfish   255 EGRTSVIETFYQLIREEGFWGLTKGLSARIISSAPTAIVMVVGYETLKKLSLRPELVDSRHW 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5805	NP_001287513.1	Mito_carr	46..125	CDD:395101	32/78 (41%)
		Mito_carr	132..238	CDD:395101	50/116 (43%)
		Mito_carr	245..327	CDD:395101	34/81 (42%)
slc25a44b	NP_001013537.1	PTZ00169	17..304	CDD:240302	120/298 (40%)
		Mito_carr	24..105	CDD:278578	32/80 (40%)
		Mito_carr	105..216	CDD:278578	50/122 (41%)
		Mito_carr	222..304	CDD:278578	34/81 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593547
Domainoid	1	1.000	94	1.000	Domainoid score	I7434
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14000
Inparanoid	1	1.050	257	1.000	Inparanoid score	I3135
OMA	1	1.010	-	-		QHG53612
OrthoDB	1	1.010	-	-		D1102784at2759
OrthoFinder	1	1.000	-	-		FOG0003691
OrthoInspector	1	1.000	-	-		otm24989
orthoMCL	1	0.900	-	-		OOG6_103919
Panther	1	1.100	-	-	LDO	PTHR46314
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5353
SonicParanoid	1	1.000	-	-		X2129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.900