DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5805 and slc25a44

DIOPT Version :9

Sequence 1:	NP_001287513.1	Gene:	CG5805 / 42950	FlyBaseID:	FBgn0039223	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001008081.1	Gene:	slc25a44 / 493443	XenbaseID:	XB-GENE-1009006	Length:	313	Species:	Xenopus tropicalis

Alignment Length:	322	Identity:	128/322 - (39%)
Similarity:	191/322 - (59%)	Gaps:	26/322 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 IRTIEWDMMNKTKFFPLSMLSSFSVRCCLFPLTVIKTQLQVQHKSDVYKGMVDCAMKIYRSEGVP 93
            |:.|||:.::|.||:...:..:..:|..::|.|:|:|:||||....:|.|..|..:||.|:||..
Frog     7 IQIIEWEHLDKKKFYVFGVCMTMIIRVSVYPFTLIRTRLQVQKGKSLYNGTFDAFVKILRTEGAA 71

  Fly    94 GLYRGFWISSVQIVSGVFYISTYEGVRHVLNDLGAGHRMKALAGGGCASLVGQTIIVPFDVISQH 158
            |.||||.:::..::||..|::|||..|..::...:.:.:|:|..||.||||.|:|.||.||:|||
Frog    72 GFYRGFLVNTFTLISGQCYVTTYELTRKYVSKYSSSNTVKSLVAGGSASLVAQSITVPIDVVSQH 136

  Fly   159 AMVLGMSAHAGSKGDINPLGIKSWPGRSRLHI-----------SMDIGREIMRRDGFRGFYRGYT 212
            .|:       ..||:.        .||.|:|.           :.||..:|.|.||||||||||.
Frog   137 LMM-------QRKGES--------MGRFRVHATDGKQPVMFGQTKDIILQIFRADGFRGFYRGYV 186

  Fly   213 ASLMAYVPNSAMWWAFYHLYQDELFRICPVWVSHLFIQCVAGSLGGFTTTILTNPLDIVRARLQV 277
            |||:.|:||||:||.|||||.::|.|:.|....||.:|.:||.|...|.:.:|||:|::|||:||
Frog   187 ASLLTYIPNSAVWWPFYHLYAEQLSRLSPNDCPHLLLQAIAGPLAAATASTITNPMDVIRARVQV 251

  Fly   278 HRLDSMSVAFRELWQEEKLNCFFKGLSARLVQSAAFSFSIILGYETIKRIAVDEQYKHQIRW 339
            ....|:...||:|..||......||||||::.|...:..|::||||:|::::..:......|
Frog   252 EGKSSIINTFRQLMAEEGPWGLTKGLSARIISSTPSTIVIVVGYETLKKLSLRPELVDSRHW 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5805	NP_001287513.1	Mito_carr	46..125	CDD:395101	29/78 (37%)
		Mito_carr	132..238	CDD:395101	54/116 (47%)
		Mito_carr	245..327	CDD:395101	35/81 (43%)
slc25a44	NP_001008081.1	Mito_carr	21..103	CDD:365909	29/81 (36%)
		Mito_carr	108..213	CDD:365909	54/119 (45%)
		Mito_carr	219..301	CDD:365909	35/81 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	96	1.000	Domainoid score	I7265
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H14000
Inparanoid	1	1.050	247	1.000	Inparanoid score	I3187
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1102784at2759
OrthoFinder	1	1.000	-	-		FOG0003691
OrthoInspector	1	1.000	-	-		oto105469
Panther	1	1.100	-	-	LDO	PTHR46314
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5353
SonicParanoid	1	1.000	-	-		X2129
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.190