DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5805 and aralar1

DIOPT Version :9

Sequence 1:	NP_001287513.1	Gene:	CG5805 / 42950	FlyBaseID:	FBgn0039223	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001247368.1	Gene:	aralar1 / 43616	FlyBaseID:	FBgn0028646	Length:	707	Species:	Drosophila melanogaster

Alignment Length:	333	Identity:	77/333 - (23%)
Similarity:	138/333 - (41%)	Gaps:	64/333 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 VGGAAEGATYIRTIEWDMMNKTKFFPLSMLSSFSVRCCLFPLTVIKTQLQVQHKSD-----VYKG 78
            |...|:.:.:|:.:|     .:..|.|...:.......::|:.::||::|.|....     .|:.
  Fly   339 VESPADRSAFIQVLE-----SSYRFTLGSFAGAVGATVVYPIDLVKTRMQNQRAGSYIGEVAYRN 398

  Fly    79 MVDCAMKIYRSEGVPGLYRGFWISSVQIVSGVFYISTYEGVRHVLNDL---------GAGHRMKA 134
            ..||..|:.|.||..|||||       ::..:..::..:.::..:|||         |.......
  Fly   399 SWDCFKKVVRHEGFMGLYRG-------LLPQLMGVAPEKAIKLTVNDLVRDKLTDKKGNIPTWAE 456

  Fly   135 LAGGGCASLVGQTIIVPFDVISQHAMVLGMSAHAGSKGDINPLGIKSWPGRSRLHISMDIGREIM 199
            :..||||.........|.:::.....|.|..| :|||       |::|              .::
  Fly   457 VLAGGCAGASQVVFTNPLEIVKIRLQVAGEIA-SGSK-------IRAW--------------SVV 499

  Fly   200 RRDGFRGFYRGYTASLMAYVPNSAMWWAFY-H---LYQDELFRICPVWVSHLFIQCVAGSLGGFT 260
            |..|..|.|:|..|.|:..||.||:::..| |   :..|:      ...:|......||::.|..
  Fly   500 RELGLFGLYKGARACLLRDVPFSAIYFPTYAHTKAMMADK------DGYNHPLTLLAAGAIAGVP 558

  Fly   261 TTILTNPLDIVRARLQVHRLDSMSV------AFRELWQEEKLNCFFKGLSARLVQSAAFSFSIIL 319
            ...|..|.|:::.||||......:.      |.:::..||....|:||.:||:.:|:......::
  Fly   559 AASLVTPADVIKTRLQVVARSGQTTYTGVWDATKKIMAEEGPRAFWKGTAARVFRSSPQFGVTLV 623

  Fly   320 GYETIKRI 327
            .||.::|:
  Fly   624 TYELLQRL 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5805	NP_001287513.1	Mito_carr	46..125	CDD:395101	17/83 (20%)
		Mito_carr	132..238	CDD:395101	27/109 (25%)
		Mito_carr	245..327	CDD:395101	22/87 (25%)
aralar1	NP_001247368.1	EF-hand_7	35..99	CDD:290234
		EF-hand_8	51..99	CDD:290545
		EF-hand_7	81..134	CDD:290234
		EFh	84..135	CDD:298682
		EF-hand_7	111..173	CDD:290234
		Mito_carr	350..448	CDD:278578	23/109 (21%)
		PTZ00169	358..631	CDD:240302	72/307 (23%)
		Mito_carr	449..539	CDD:278578	27/111 (24%)
		Mito_carr	544..633	CDD:278578	23/88 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441539
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840