DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5805 and Slc25a44

DIOPT Version :9

Sequence 1:	NP_001287513.1	Gene:	CG5805 / 42950	FlyBaseID:	FBgn0039223	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001102417.1	Gene:	Slc25a44 / 365841	RGDID:	1307244	Length:	337	Species:	Rattus norvegicus

Alignment Length:	322	Identity:	127/322 - (39%)
Similarity:	200/322 - (62%)	Gaps:	9/322 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 GAAEGATYIRTIEWDMMNKTKFFPLSMLSSFSVRCCLFPLTVIKTQLQVQHKSDVYKGMVDCAMK 85
            |..||...|:.|||:.::|.||:...:..:..:|..::|.|:|:|:||||....:|.|..|..:|
  Rat    22 GNMEGKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFVK 86

  Fly    86 IYRSEGVPGLYRGFWISSVQIVSGVFYISTYEGVRHVLNDLGAGHRMKALAGGGCASLVGQTIIV 150
            |.|::||.||||||.:::..::||..|::|||..|..:.|....:.:|:|..||.||||.|:|.|
  Rat    87 ILRADGVTGLYRGFLVNTFTLISGQCYVTTYELTRKFVADYSQSNTVKSLVAGGSASLVAQSITV 151

  Fly   151 PFDVISQHAMVLGMSAHAGS---KGDINPLGIKSWPGRSRLHISMDIGREIMRRDGFRGFYRGYT 212
            |.||:|||.|:.......|.   :|::...|:.:: |:::     ||.|:|:|.||.|||||||.
  Rat   152 PIDVVSQHLMMQRKGEKMGRFQVRGNLEGQGLIAF-GQTK-----DIIRQILRADGLRGFYRGYV 210

  Fly   213 ASLMAYVPNSAMWWAFYHLYQDELFRICPVWVSHLFIQCVAGSLGGFTTTILTNPLDIVRARLQV 277
            |||:.|:||||:||.|||.|.::|.|:||....|:..|.::|.|...|.::||||:|::|.|:||
  Rat   211 ASLLTYIPNSAVWWPFYHFYAEQLSRLCPQECPHIVFQAISGPLAAATASVLTNPMDVIRTRVQV 275

  Fly   278 HRLDSMSVAFRELWQEEKLNCFFKGLSARLVQSAAFSFSIILGYETIKRIAVDEQYKHQIRW 339
            ....|:.:.||:|..||......||||||::.:...:..|::|||::|::::..:......|
  Rat   276 EGKSSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKKLSLRPELVDSRHW 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5805	NP_001287513.1	Mito_carr	46..125	CDD:395101	30/78 (38%)
		Mito_carr	132..238	CDD:395101	51/108 (47%)
		Mito_carr	245..327	CDD:395101	31/81 (38%)
Slc25a44	NP_001102417.1	PTZ00169	43..325	CDD:240302	117/287 (41%)
		Mito_carr	<58..128	CDD:278578	30/69 (43%)
		Mito_carr	128..237	CDD:278578	51/114 (45%)
		Mito_carr	250..325	CDD:278578	29/74 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351729
Domainoid	1	1.000	99	1.000	Domainoid score	I6982
eggNOG	1	0.900	-	-		E1_KOG0765
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14000
Inparanoid	1	1.050	258	1.000	Inparanoid score	I3060
OMA	1	1.010	-	-		QHG53612
OrthoDB	1	1.010	-	-		D1102784at2759
OrthoFinder	1	1.000	-	-		FOG0003691
OrthoInspector	1	1.000	-	-		oto98774
orthoMCL	1	0.900	-	-		OOG6_103919
Panther	1	1.100	-	-	LDO	PTHR46314
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2129
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770