DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42331 and cd

DIOPT Version :9

Sequence 1:	NP_001189281.1	Gene:	CG42331 / 42948	FlyBaseID:	FBgn0259233	Length:	1615	Species:	Drosophila melanogaster
Sequence 2:	NP_651081.1	Gene:	cd / 42681	FlyBaseID:	FBgn0263986	Length:	830	Species:	Drosophila melanogaster

Alignment Length:	829	Identity:	257/829 - (31%)
Similarity:	385/829 - (46%)	Gaps:	139/829 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLVALLLLLV---HLENASGKP--------PTKELPRPLIPLHDQDQEEELQPELEAKATFQSTR 59
            :..||.|.||   .|..|.|.|        ...|| .|..||.|:...|.
  Fly    59 VFTALCLALVFSDSLGGADGGPSFFFVVNGSDSEL-APNRPLPDEPAAEW--------------- 107

  Fly    60 NGRSRRPTLMDVAL-----QQSVRQGLDAMTELYGRIQPEMLRNG-QTLQDNHPAAMLSRFNAPT 118
                   .|...||     .|:|..|:.|:.:      .|:|..| |..:.|.|:  ...:.:.:
  Fly   108 -------ALQQAALGHHDGAQAVSAGIKALGD------REILEEGLQPNEVNTPS--FRHYRSLS 157

  Fly   119 TDSERREMAAYATIAAAKAFRKNFQHIDELARQSHTQRISLRRTALEGLCPPRD----------P 173
            |:.|.|::       |.:.:.:|...||...|.::|::            |.|.          |
  Fly   158 TNPEARKL-------ARRGYVENQATIDIAKRFNYTKQ------------PGRSNIGWGPKIVLP 203

  Fly   174 PPCMPASE-----RYRTHDGTCNNKRRPR-WGAAQMPFNRFLPPEYGDGVDTVRSSADGSTLSSS 232
            .|.:...|     |||...|.||||:.|| :||:.:|:.|.:.|:|.||:...|.|..| .|..:
  Fly   204 DPTVLRLECDFNARYRRSTGVCNNKQHPRTYGASMVPYRRMVSPDYADGIAAPRVSHHG-RLPPA 267

  Fly   233 RFVSLLVH-GAREGEAPLTLMIAQWGQMLDHDMTSTAQPRSINGSIPSCC--GGKDFHPACFPIK 294
            |.|||.:| .:.|.::..|:|:|.:||.:|||:|:|:...|..|....||  ..::.||.|:|:.
  Fly   268 RQVSLKIHRSSYETDSNFTVMLAVFGQFMDHDITATSLTTSQEGESIDCCVAATREQHPECYPVD 332

  Fly   295 VPLDDPWLAPLKVRCLEFLRSAPAQRRDCVLSWREQTNQVTSYIDASPIYSNSAKSSDNARVFRH 359
            :..|||:.....:.|:.|:|||||....  ...|.|.||.|::||||.:|.|..:..:..|.|.:
  Fly   333 ILPDDPYYKQYNISCMNFVRSAPAPTGR--FGPRMQLNQATAFIDASVVYGNLEQRQNQLRSFIN 395

  Fly   360 GLLVY-----GR------GDPAEDVCQR---GAIATKCIRSGDGRSGEQPGLLAMHHVWVGEHNR 410
            |.|..     ||      .:|| |.|.|   ..:...|..|||.|:.|...|.:||.:|...||.
  Fly   396 GSLRMFVTDDGRQLLPISSNPA-DGCNRVQMTRLGKYCFESGDDRANENLLLTSMHLLWARHHNY 459

  Fly   411 IAMELSELNPHWSDEKVYQETRRIVGAMFQHITFREFLPVILGREVVKLFDLELMPSGYY----E 471
            :|.:|.|.||||.||::|||.|:|:||...|||:.|||||:||:.:.:.  ..|:|:.:.    :
  Fly   460 LARQLQEQNPHWEDERLYQEARKILGAQMAHITYNEFLPVLLGKNISEA--KGLLPAKHNLNAPD 522

  Fly   472 RYSSKVNPTVANAFAAAAFRFGHSLV--------QNSYTRCDRHHNVINNNVSLHEEFQRGDIGS 528
            .|..:|:|::||.||||||||.|:|:        .||.......|.::.|..||..|.
  Fly   523 TYDPEVDPSIANCFAAAAFRFAHTLLPGLFNISRDNSTPEAIELHKMLFNPFSLWAEH------- 580

  Fly   529 AGSLHRLLRGLASQRALKRDEFITPELTNHLFQTPG---FPF-GLDLAAINIQRGRDHGIAPYSA 589
             |..|.|:.. |:...::.|.|.:.|:|..||:...   .|. ||||.::||||||||||..|..
  Fly   581 -GIDHALMTA-ANTPVMQVDRFFSLEVTQKLFEGTAEDRVPLCGLDLVSLNIQRGRDHGIPSYPV 643

  Fly   590 WRVPCGLSPILSWDDFANVVGPESAKRIGHAYRSVHDIDLFVGGIAERPVVGGLVGPTFACIIAQ 654
            :|..|.|..:.:|::.:..:...:...|...|.|..|:|::.|.::|.|:.|.:.||..:|:::.
  Fly   644 FRRHCRLPTVDTWEEMSQAIDNATLDSIRQIYESPQDVDVYTGALSEPPLDGAIFGPLLSCMVSD 708

  Fly   655 QFSNSRRGDRFWYENGGFESSFTPAQLHSLRRVSLAQVLCRTVGGGT-LQPHIFIPAEFEDNERQ 718
            ||...:.||..|||.......||.|||..:.:.|||.::||...|.| ::.|:........|...
  Fly   709 QFLRLKLGDSHWYERKMGPQKFTKAQLAEIYKTSLAAIICRNSDGITRVREHVMQRLRDGGNPHV 773

  Fly   719 TCGVGSLSPIDLSPWLEQDPFHNQQVPEQVFTIGQPELGSVQIIKEDKA 767
            .|........:..||.|      :|.|:.:.:.|... ||..:....||
  Fly   774 DCQDLEGFHFNFEPWSE------KQQPQDLHSAGISR-GSTSVRVMSKA 815

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42331	NP_001189281.1	An_peroxidase	183..699	CDD:281139	198/549 (36%)
CG42331	NP_001189281.1	peroxinectin_like	328..696	CDD:188655	142/397 (36%)
cd	NP_651081.1	An_peroxidase	218..755	CDD:281139	199/551 (36%)
cd	NP_651081.1	peroxinectin_like	364..750	CDD:188655	142/397 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	107	1.000	Domainoid score	I2172
eggNOG	1	0.900	-	-		E1_KOG2408
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11475
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920