Protein Alignment CG42331 and Mpo

DIOPT Version :10

• Sequence 1: NP_651282.2
• Gene: CG42331 / 42948
• FlyBaseID: FBgn0259233
• Length: 1615
• Species: Drosophila melanogaster
• Sequence 2: NP_001388741.1
• Gene: Mpo / 303413
• RGDID: 1592081
• Length: 718
• Species: Rattus norvegicus
• Alignment Length: 789
• Identity: 243/789 - (30%)
• Similarity: 366/789 - (46%)
• Gaps: 138/789 - (17%)

  Fly     7 LVALLLLLVHLENASGKPPTKELPRPLIPLHDQDQEEELQPELEAKATFQSTRNGRSRRPTLMDV 71
            |..||..|..|:.::|..|.  ||..:......|..||.: .|..||.       :.||
  Rat     7 LAGLLAPLAMLQTSTGATPA--LPGEVANSVVLDCMEEAK-RLVNKAY-------KERR------ 55

  Fly    72 ALQQSVRQGLDAMTELYGRIQPEMLRNGQTLQDNHPAAMLSRFNAPTTDSERREMAAYATIAAAK 136
               :|::|.               ||:|..    .|..:||.|..|...:.....||.....|..
  Rat    56 ---ESIKQS---------------LRSGSA----SPMELLSYFKQPVAGTRTAVRAADYLHVALD 98

  Fly   137 AFRKNFQ-------HIDELARQSHTQRISLRR-TALEGL---CPPRDPPPCMPASERYRTHDGTC 190
            ..::..|       ::.::...:....:|:.. .|.:.:   |||:|         :|||..|.|
  Rat    99 LLKRKLQPLWPRPFNVTDVLTPAQLNLLSVSSGCAYQDVGVTCPPQD---------KYRTITGHC 154

  Fly   191 NNKRRPRWGAAQMPFNRFLPPEYGDGVD-----TVRSSADGSTLSSSRFVSLLVHGAREGEAPLT 250
            ||:|.|..||:...|.|:||.||.||:.     |.:.:..|..:..:|.||..:  .|.....||
  Rat   155 NNRRSPTLGASNRAFVRWLPAEYEDGISLPFGWTPKVNRSGFKVPLARQVSNAI--VRFPNDQLT 217

  Fly   251 ------LMIAQWGQMLDHDMTSTAQPRS----ING--SIPSCCGGKDFHPACFPIKVPLDDPWLA 303
                  ||..||||.||||:|.|.:|.:    :.|  ...||..    ...|||:|:|.:||.:.
  Rat   218 KDQERALMFMQWGQFLDHDITLTPEPATRFSFLTGLNCETSCLQ----QQPCFPLKIPPNDPRIK 278

  Fly   304 PLKVRCLEFLRSAPAQRRDCV---LSWREQTNQVTSYIDASPIYSN------------------- 346
            ..| .|:.|.||.||    |.   ::.|.|.|.:||::|||.:|.:
  Rat   279 NQK-DCIPFFRSCPA----CTGSNITIRNQINALTSFVDASGVYGSEDPLARRLRNLTNQLGLLA 338

  Fly   347 -SAKSSDNARVFRHGLLVYG--RGDPAEDVCQRGAIATKCIRSGDGRSGEQPGLLAMHHVWVGEH 408
             :.:..||.|    .||.:.  ..||.  :....:....|..:||.||.|.|.|.:||.::|.||
  Rat   339 VNTRFQDNGR----ALLPFDSLHDDPC--LLTNRSARIPCFLAGDMRSSEMPELTSMHTLFVREH 397

  Fly   409 NRIAMELSELNPHWSDEKVYQETRRIVGAMFQHITFREFLPVILGREVVKLFDLELMPSGYYERY 473
            ||:|.||..|||.|:.||:|||.|:|||||.|.||:|::||::||...:|.:    :|.  |..|
  Rat   398 NRLATELKRLNPRWNGEKLYQEARKIVGAMVQIITYRDYLPLVLGPAAMKKY----LPQ--YRSY 456

  Fly   474 SSKVNPTVANAFAAAAFRFGHSLVQNSYTRCDRHHNVI--NNNVSLHEE-FQRGDIGSAGSLHRL 535
            :..|:|.:||.| ..|||:||:|:|....|.|..:...  |..|.|... |....:...|.:..:
  Rat   457 NDSVDPRIANVF-TNAFRYGHTLIQPFMFRLDNQYRSTGPNPRVPLSRVFFASWRVVLEGGIDPI 520

  Fly   536 LRGLASQRAL--KRDEFITPELTNHLFQTPGFPFGLDLAAINIQRGRDHGIAPYSAWRVPCGLSP 598
            ||||.:..|.  ::::....|:...||:.. ...||||.|:|:||.||||:..|:|||..|||..
  Rat   521 LRGLMATPAKLNRQNQIAVDEIRERLFEQV-MRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQ 584

  Fly   599 ILSWDDFANVV-GPESAKRIGHAYRSVHDIDLFVGGIAERPVVGGLVGPTFACIIAQQFSNSRRG 662
            ..:..:...|: ..|.|:::...|.:.::||:::||::|.....|.||...||:|..||...|.|
  Rat   585 PSTVGELGTVLKNLELARKLMAQYGTPNNIDIWMGGVSEPLEPNGRVGQLLACLIGTQFRKLRDG 649

  Fly   663 DRFWYENGGFESSFTPAQLHSLRRVSLAQVLCRTVGGGTL-QPHIFIPAEFEDNERQTCGVGSLS 726
            ||||:||.|.   |:..|..:|..:||.:::|...|..|: :.:||:.   ..:.|......:|.
  Rat   650 DRFWWENPGV---FSKQQRQALATISLPRIICDNTGITTVSKNNIFMS---NSHPRDFVSCNTLP 708

  Fly   727 PIDLSPWLE 735
            .::|:.|.|
  Rat   709 KLNLASWKE 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42331	NP_651282.2	An_peroxidase	183..707	CDD:460804	199/572 (35%)
		LHP1	731..>871	CDD:227520	2/5 (40%)
Mpo	NP_001388741.1	myeloperoxidase_like	289..702	CDD:188656	148/436 (34%)