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Protein Alignment CG42331 and pxn-1

DIOPT Version :10

Sequence 1:	NP_651282.2	Gene:	CG42331 / 42948	FlyBaseID:	FBgn0259233	Length:	1615	Species:	Drosophila melanogaster
Sequence 2:	NP_505188.3	Gene:	pxn-1 / 191484	WormBaseID:	WBGene00004256	Length:	1285	Species:	Caenorhabditis elegans

Alignment Length:	757	Identity:	237/757 - (31%)
Similarity:	357/757 - (47%)	Gaps:	108/757 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 EAKATFQSTRNGRSRRPTLMDV---ALQQSVRQGLD-AMTELYGRIQPEMLRNGQTLQDNHPAAM 110
            :||.|.......::..|.:.:.   |:.|..||.:: |:.:...::..:.:.|...|:      .
Worm   491 DAKLTVIGGETRKAAAPQIDEELLRAIAQKARQNVENAVEKTRKQLTQDKVTNTNDLK------R 549

  Fly   111 LSRFNAPTTD---SERREMAAYATIAAAKAFRKN-FQHIDELARQSHTQRISLRRT--------- 162
            |.||:.|...   |:.||:...:.....:...|. ..::|||    |.:.:|....
Worm   550 LFRFSTPKQAVELSKAREIYEESVRLVREHVEKGLILNVDEL----HPKNVSYESVLHVTHVQAL 610

  Fly   163 -ALEGLCPPRDPPPCMPA--SERYRTHDGTCNNKRRPRWGAAQMPFNRFLPPEYGDGVDT----- 219
             .|.|....:...||...  ..|||:.||.||||.:|..|.:.||..|.|.|.|.:|.:|
Worm   611 MGLSGCHTGQYKNPCTDTCFHHRYRSFDGQCNNKNKPMTGVSLMPLRRLLKPVYENGFNTPVGWE 675

  Fly   220 VRSSADGSTLSSSRFVS-LLVHGAREGEAP---LTLMIAQWGQMLDHDMTS--TAQPRSINGSIP 278
            .....:|..|.:.|.|| .||  |.|...|   |:.|:.||||.:|||:|.  ||..|....:..
Worm   676 KGRLYNGYPLPNVREVSRQLV--ATENITPHSKLSSMVMQWGQFVDHDLTHTVTALSRHSYATGA 738

  Fly   279 SC---CGGKDFHPACFPIKVPLDDPWL--APLKVRCLEFLRSAPAQRRDC----------VLSWR 328
            .|   |...|   .||.|.:..:||.:  ...|..|:||.|||..    |          .:::|
Worm   739 FCNRTCENLD---PCFNIPLSPNDPRVKSGSAKYPCIEFERSAAV----CGSGETSLVFNRVTYR 796

  Fly   329 EQTNQVTSYIDASPIY-SNSAKSSDNARVF-RHGLLVYGRGDPAEDV--------------CQRG 377
            ||.|.:||::|||.:| ||..::.:....: .:|:|   |.|...:.              |:|.
Worm   797 EQMNALTSFLDASNVYGSNEVQAQELRDTYNNNGML---RFDITSEAGKEYLPFEKDSNMDCRRN 858

  Fly   378 ---AIATKCIRSGDGRSGEQPGLLAMHHVWVGEHNRIAMELSELNPHWSDEKVYQETRRIVGAMF 439
               ....:|..:||.|:.||..|.|.|.:::.||||||.:|..:|.:|..|.:|.|||:|||||.
Worm   859 FSEENPIRCFLAGDLRANEQLALAATHTIFIREHNRIAKKLKSMNGNWDGEIIYHETRKIVGAMM 923

  Fly   440 QHITFREFLPVILGREV-VKLFDLELMPSGYYERYSSKVNPTVANAFAAAAFRFGHSLVQNSYTR 503
            ||||::.::|:|.|.:. :..|      .|.|:.|...|:.:|.||||.|||||||:::..|..|
Worm   924 QHITYKHWMPIIFGGQAQMNKF------VGTYQGYDPDVDASVTNAFATAAFRFGHTIINPSLFR 982

  Fly   504 CDRHHNVI-NNNVSLHEEFQRGD-IGSAGSLHRLLRGLASQRALKR---DEFITPELTNHLFQTP 563
            .......| ..:::||:.|...: :.:.|.:..|||||.:. .||.   .:.:..||...||. .
Worm   983 LGNDFMPIKEGHIALHKAFFTPELVLTQGGVDPLLRGLFAS-PLKHPMPTQLLNMELIEKLFM-K 1045

  Fly   564 GFPFGLDLAAINIQRGRDHGIAPYSAWRVPCGLSPILSWDDFANVVGPES-AKRIGHAYRSVHDI 627
            |....||||.:||||.||||:..|:.:|..|.|...:.|:|....:..:. .:::...|....:|
Worm  1046 GHEVSLDLAVMNIQRSRDHGLPSYTEYRKFCNLPVPVQWEDMKGYIKDDMIIQKLRGLYGVPQNI 1110

  Fly   628 DLFVGGIAERPVVGGLVGPTFACIIAQQFSNSRRGDRFWYENGGFESSFTPAQLHSLRRVSLAQV 692
            ||:||||.|..:..||.||||||||.:||...|.|||||||..|.   |||.||..:::::||::
Worm  1111 DLWVGGIVEEKLENGLFGPTFACIIGEQFRKIRDGDRFWYEKDGV---FTPEQLREIKKITLARL 1172

  Fly   693 LCRTVGG-GTLQPHIFIPAEFEDNERQTCGVGSLSPIDLSPW 733
            .|..... ..:|..:|:....:.....||....:  ::|..|
Worm  1173 FCDNGDNIDRIQKDVFMYPGMDKENYGTCQETEM--MNLRAW 1212

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.