Protein Alignment CG42331 and Mpo

DIOPT Version :10

• Sequence 1: NP_651282.2
• Gene: CG42331 / 42948
• FlyBaseID: FBgn0259233
• Length: 1615
• Species: Drosophila melanogaster
• Sequence 2: NP_034954.2
• Gene: Mpo / 17523
• MGIID: 97137
• Length: 718
• Species: Mus musculus
• Alignment Length: 744
• Identity: 243/744 - (32%)
• Similarity: 358/744 - (48%)
• Gaps: 93/744 - (12%)

  Fly    49 LEAKATFQSTRNGRSRRPTLMDVALQQSVRQGLDAMTELYGRIQPEMLRN-GQTLQDN--HPAAM 110
            |.|......|.||.:  |.|:.......|...::...:|..|...|...: .::||..  .|..:
Mouse    10 LLAPLAMLQTSNGAT--PALLGEVENSVVLSCMEEAKQLVDRAYKERRESIKRSLQSGSASPTEL 72

  Fly   111 LSRFNAPTTDSERREMAA-YATIAAAKAFRK-------NFQHIDELARQSHTQRISLRRTALEGL 167
            |..|..|...:.....|| |..:|.....||       .|...|.|.      ...|...::...
Mouse    73 LFYFKQPVAGTRTAVRAADYLHVALDLLKRKLQPLWPRPFNVTDVLT------PAQLNLLSVSSG 131

  Fly   168 CPPRDPPPCMPASERYRTHDGTCNNKRRPRWGAAQMPFNRFLPPEYGDGVD-----TVRSSADGS 227
            |..:|.....|.:::|||..|.|||:|.|..||:...|.|:||.||.|||.     |...:.:|.
Mouse   132 CAYQDVRVTCPPNDKYRTITGHCNNRRSPTLGASNRAFVRWLPAEYEDGVSMPFGWTPGVNRNGF 196

  Fly   228 TLSSSRFVSLLVHGAREGEAPLT------LMIAQWGQMLDHDMTSTAQPRS-------INGSIPS 279
            .:..:|.||..:  .|.....||      ||..||||.||||:|.|.:|.:       :|.. .|
Mouse   197 KVPLARQVSNAI--VRFPNDQLTKDQERALMFMQWGQFLDHDITLTPEPATRFSFFTGLNCE-TS 258

  Fly   280 CCGGKDFHPACFPIKVPLDDPWLAPLKVRCLEFLRSAPAQRRDCVLSWREQTNQVTSYIDASPIY 344
            |..    .|.|||:|:|.:||.:...| .|:.|.||.||..|:.: :.|.|.|.:||::|||.:|
Mouse   259 CLQ----QPPCFPLKIPPNDPRIKNQK-DCIPFFRSCPACTRNNI-TIRNQINALTSFVDASGVY 317

  Fly   345 SNSAKSSDN-ARVFRH-----GLLVY-------GRG----DPAED----VCQRGAIATKCIRSGD 388
            .    |.|. ||..|:     |||..       ||.    |...|    :..|.| ...|..:||
Mouse   318 G----SEDPLARKLRNLTNQLGLLAINTRFQDNGRALMPFDSLHDDPCLLTNRSA-RIPCFLAGD 377

  Fly   389 GRSGEQPGLLAMHHVWVGEHNRIAMELSELNPHWSDEKVYQETRRIVGAMFQHITFREFLPVILG 453
            .||.|.|.|.:||.::|.||||:|.:|..|||.|:.||:|||.|:|||||.|.||:|::||::||
Mouse   378 MRSSEMPELTSMHTLFVREHNRLATQLKRLNPRWNGEKLYQEARKIVGAMVQIITYRDYLPLVLG 442

  Fly   454 REVVKLFDLELMPSGYYERYSSKVNPTVANAFAAAAFRFGHSLVQNSYTRCDRHHNVI--NNNVS 516
            ...:|.:    :|.  |..|:..|:|.:||.| ..|||:||:|:|....|.:..:...  |..|.
Mouse   443 PAAMKKY----LPQ--YRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLNNQYRPTGPNPRVP 500

  Fly   517 LHEE-FQRGDIGSAGSLHRLLRGLASQRAL--KRDEFITPELTNHLFQTPGFPFGLDLAAINIQR 578
            |.:. |....:...|.:..:||||.:..|.  ::::.:..|:...||:.. ...||||.|:|:||
Mouse   501 LSKVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIVVDEIRERLFEQV-MRIGLDLPALNMQR 564

  Fly   579 GRDHGIAPYSAWRVPCGLSPILSWDDFANVV-GPESAKRIGHAYRSVHDIDLFVGGIAERPVVGG 642
            .||||:..|:|||..|||....:..:...|: ..|.|:::...|.:.::||:::||::|.....|
Mouse   565 SRDHGLPGYNAWRRFCGLPQPSTVGELGTVLKNLELARKLMAQYGTPNNIDIWMGGVSEPLEPNG 629

  Fly   643 LVGPTFACIIAQQFSNSRRGDRFWYENGGFESSFTPAQLHSLRRVSLAQVLCRTVGGGTL-QPHI 706
            .||...||:|..||...|.|||||:||.|.   |:..|..:|..:||.:::|...|..|: :.:|
Mouse   630 RVGQLLACLIGTQFRKLRDGDRFWWENPGV---FSKQQRQALASISLPRIICDNTGITTVSKNNI 691

  Fly   707 FIPAEFEDNERQTCGVGSLSPIDLSPWLE 735
            |:...:   .|......:|..::|:.|.|
Mouse   692 FMSNTY---PRDFVSCNTLPKLNLTSWKE 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42331	NP_651282.2	An_peroxidase	183..707	CDD:460804	206/569 (36%)
		LHP1	731..>871	CDD:227520	2/5 (40%)
Mpo	NP_034954.2	myeloperoxidase_like	289..702	CDD:188656	153/432 (35%)