Protein Alignment CG42331 and Duox

DIOPT Version :10

• Sequence 1: NP_651282.2
• Gene: CG42331 / 42948
• FlyBaseID: FBgn0259233
• Length: 1615
• Species: Drosophila melanogaster
• Sequence 2: XP_319115.5
• Gene: Duox / 1279399
• VectorBaseID: AGAMI1_000295
• Length: 1511
• Species: Anopheles gambiae
• Alignment Length: 900
• Identity: 221/900 - (24%)
• Similarity: 352/900 - (39%)
• Gaps: 240/900 - (26%)

  Fly   130 ATIAAAKAFRKNFQHIDELARQSHTQRISLRRTALEGLCPPRDPPPCMPASERYRTHDGTCNNKR 194
            ||:.||           |.:..||.::                        :||   ||..||..
Mosquito    27 ATVGAA-----------ESSLMSHVEK------------------------QRY---DGWYNNLA 53

  Fly   195 RPRWGAAQMPFNRFLPPEYGDGVDTVRSSADGSTLSSSRFVSLLVHGAREGEAPL---TLMIAQW 256
            .|.|||......|..|..|.|||..:.    ||...|.|.:|.|.....:|...:   |.::|.:
Mosquito    54 HPDWGAVDNHLTRKAPSAYSDGVYVMA----GSNRPSPRKLSRLFMRGTDGLPSMENRTALLAFF 114

  Fly   257 GQMLDHDMTSTAQ---PRSING-SIPSC-------CGGK---DFHPACFPIKVPLDDPWLAPLKV 307
            ||::.:::...::   |..::. .|..|       |.|.   .||.|.:.     .:...:|
Mosquito   115 GQVVTNEIVMASESGCPIEMHRIEIEKCDEMYDRECRGDRYIPFHRAAYD-----RNTGQSP--- 171

  Fly   308 RCLEFLRSAPAQRRDCVLSWREQTNQVTSYIDASPIYSNSAKSSDNARVFRHGLLVYGR------ 366
                   :||          |||.||:|::||.|.|||.|....:..|.|:.|.|:..:
Mosquito   172 -------NAP----------REQINQMTAWIDGSFIYSTSEAWLNAMRSFQDGALLTDKQGTMPV 219

  Fly   367 ---------GDPAEDVCQRGAIATKCIRSGDGRSGEQPGLLAMHHVWVGEHNRIAMELSELNPHW 422
                     .:|...| .|.....:....||.|:.:.|.||:...:::..||.:|..:...:..|
Mosquito   220 KNTMRVPLFNNPVPHV-MRMLSPERLYLLGDPRTNQNPALLSFAILFLRWHNVVAKRVRRQHRDW 283

  Fly   423 SDEKVYQETRRIVGAMFQHITFREFLPVILGREVVKLFDLELMPSGYYERYSSKVNPTVANAFAA 487
            |||:::|..||:|.|..|:|...|:||..|        |.|:.|   |:.|.:..:|.|::.|.|
Mosquito   284 SDEEIFQRARRVVIASLQNIVAYEYLPAFL--------DKEIPP---YDGYKADTHPGVSHMFQA 337

  Fly   488 AAFRFGHSLVQNSYTRCDRHHNVINNNVSL------HEEFQRGDIGSAGSLHRLLRGLASQRALK 546
            |||||||||:.....|.|...|....|:..      ...:...|:.....:...:.|:|||.|.|
Mosquito   338 AAFRFGHSLIPPGLFRRDGQCNFRRTNMDFPALRLCSTWWNSNDVLDNTPVEEFIMGMASQIAEK 402

  Fly   547 RDEFITPELTNHLFQTPGFPFGLDLAAINIQRGRDHGIAPYSAWRVPCGLSPILSWDDFANVV-- 609
            .|..:..::.:.||....|. ..||.|:||.||||:|:..|:..|....|....||.|....|
Mosquito   403 EDPLLCSDVRDKLFGPMEFT-RRDLGALNIMRGRDNGLPDYNTARAAYRLPKKKSWRDINPAVFE 466

  Fly   610 -GPESAKRIGHAY-RSVHDIDLFVGGIAERPVVGGLVGPTFACIIAQQFSNSRRGDRFWYENGGF 672
             .||....:...| ..:.::|::|||:.|.   .|..|..|:.:|..||:..|..||||:||..
Mosquito   467 RQPELLDLLIKTYDNQLDNVDVYVGGMLES---DGRPGELFSAVIIDQFTRIRDADRFWFENED- 527

  Fly   673 ESSFTPAQLHSLRRVSLAQVLCRTVGGGTLQPHIFIPAEFEDNERQTCGVGSLSPIDLSPWLEQD 737
            ...||..::..:|:.:|..::..:             .:.|.:|.|.         |:..|.:.|
Mosquito   528 NGIFTKEEIAEIRKFTLWDIIVNS-------------TDIEADEIQR---------DVFHWKQGD 570

  Fly   738 PFHNQQVPEQV-FTIGQP----------------------ELGSVQIIKEDKAGF------SNRV 773
            |...   |||: .|:.:|                      .||.|.|:... ||:      ::|.
Mosquito   571 PCPQ---PEQLNATLLEPCNYLEGYDYFSGSELAYIYSCVFLGFVPILCAG-AGYCVIKLQNSRR 631

  Fly   774 KPIKPQVEVSPSSLSGFHRPTNENLTKVSDKLDLRRKTVTKKNNTNNRQQTTRK--PVGGVNNKL 836
            :.:|.:.|...::.:          ||||.:..:.|:.:    :.|:::..|.|  |...:....
Mosquito   632 RKLKIKQEAMKNTAN----------TKVSVEKMVAREWL----HANHKRLVTVKFGPEASIYTVD 682

  Fly   837 DKSPKI-TLNIKSVNV----RRPEGSGLKRRVIINNVP------VELRSSGGNATAEETEPGNLT 890
            .|..|: |.|:|.|:|    :..|....|:..|:..||      :||.|:....
Mosquito   683 RKGEKLRTFNLKHVDVVTVEQSQENYTAKKPYILLRVPNDHDLVLELESNSARR----------- 736

  Fly   891 DEDDEFHDDAGEVVDMEDIVEVRASKDDPSKLTKTDLNQNRN----DSKTTETEQ 941
                :|      |..:||.:.:.       |.|.|.:..||:    .::|.|..|
Mosquito   737 ----KF------VKKLEDFLVLH-------KKTMTFVESNRDLMLAKAETRERRQ 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42331	NP_651282.2	An_peroxidase	183..707	CDD:460804	156/565 (28%)
		LHP1	731..>871	CDD:227520	38/181 (21%)
Duox	XP_319115.5	None